Clinical Trials in Detroit

Showing 6641-6660 of 19,719 trials

3T MRI Versus MR Arthrogram in SLAP Lesions

NCT01896947

The purpose of this study is to evaluate the diagnostic performance of three Tesla magnetic resonance imaging (3T MRI) compared to magnetic resonance arthrogram (MR arthrogram) in diagnosing superior labrum anterior posterior (SLAP) lesions. We hypothesize that 3T MRI will have non-inferior sensitivity compared to MR arthrogram in diagnosing SLAP lesions utilizing arthroscopy as our gold standard test. To evaluate our hypothesis, the investigators will include patients suspected to have a SLAP lesion on history and physical examination by a fellowship trained orthopaedic surgery. Patients will be offered advanced imaging (both 3T MRI and MR arthrogram) as well as arthroscopy for definitive diagnosis and treatment after consent is obtained. A fellowship trained musculoskeletal radiologist will perform and interpret the magnetic resonance tests while the arthroscopy will be performed by orthopaedic surgeons. The diagnostic characteristics of each imaging modality, including sensitivity, specificity, negative predictive value, and positive predictive value, will be compared to each other.

Superior Labrum Anterior Posterior Lesion

Henry Ford Health SystemStarted Sep 2024

Detroit, Michigan, United States

TERMINATEDPhase 3< 1 mile

Randomized Global Phase 3 Study to Evaluate the Impact on NASH With Fibrosis of Obeticholic Acid Treatment

NCT02548351

The primary objectives of this study are to evaluate the effect of Obeticholic Acid treatment compared to placebo on 1) histological improvement and 2) liver-related clinical outcomes in patients with non-cirrhotic nonalcoholic steatohepatitis (NASH) with liver fibrosis.

Non Alcoholic Steatohepatitis (NASH)

Intercept Pharmaceuticals2,477 participantsStarted Sep 2015

Birmingham, Alabama, United States • Dothan, Alabama, United States • Chandler, Arizona, United States +343 more locations

3T MRI Versus MR Arthrogram in SLAP Lesions

Randomized Global Phase 3 Study to Evaluate the Impact on NASH With Fibrosis of Obeticholic Acid Treatment

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Study to Evaluate the Safety and Efficacy of Lenacapavir (GS-6207) in Combination With Other Antiretroviral Agents in People Living With HIV

Sleep To Reduce Incident Depression Effectively

The MOTION Study - Treatment of LSS With the MILD Procedure

Post-Market Study to Assess Outcomes of Patients Treated With AFX System Compared to Other EVAR Devices

Dose De-escalation Study of the PI3k Alpha/Delta Inhibitor, Copanlisib Given in Combination With the Immunotherapeutic Agents, Nivolumab and Rituximab in Patients With Relapsed/Refractory Indolent Lymphoma

SCD for CRS in Congestive Heart Failure (CHF) (No Left Ventricular Assist Device)

Evaluation of a Diagnostic Device for Detection of Nasal Staphylococcus Aureus

Safety and Tolerability of GTX-104 Compared with Oral Nimodipine in Patients with ASAH

Ravulizumab in Thrombotic Microangiopathy Associated With a Trigger

Safety and Performance of PEEK Anchors in Extremities

Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumors

Inspiring New Science In Guiding Healthcare in Turner Syndrome Registry

A Study of Anti-PD-L1 Checkpoint Antibody (LY3300054) Alone and in Combination in Participants With Advanced Refractory Solid Tumors

Intravascular Ultrasound-Guided Intervention for Venous Leg Ulcers (IGuideU)

Assessment of 3M Oedema Reduction System in the Treatment of Lymphoedema Compared to Commercial Short-stretch Bandage

Treatment Efforts Addressing Child Weight Management by Unifying Patients, Parents & Providers

A Comparison of an Investigational Dressing to Tegaderm Matrix Wound Dressing in the Management of Diabetic Foot Ulcers

Enabling Personalized Medicine Through Exome Sequencing in the U.S. Air Force