Clinical Trials in Detroit

Showing 6441-6460 of 14,997 trials

A Study of BMS-863233 in Patients With Advanced and/or Metastatic Solid Tumors

NCT00886782

The purpose of this study is to determine safety, tolerability and maximum tolerated dose of BMS-863233 in subjects advanced and/or Metastatic solid tumors.

Advanced Solid CancersMetastatic Cancer

Bristol-Myers Squibb11 participantsStarted May 2009

Boston, Massachusetts, United States • Boston, Massachusetts, United States • Detroit, Michigan, United States +3 more locations

TERMINATEDPhase 2< 1 mile

Targeted T Cells After Neoadjuvant Chemotherapy in Treating Women With Stage II or III Breast Cancer Undergoing Surgery

NCT01147016

RATIONALE: Neoadjuvant chemotherapy for women with stage II-III Her negative breast cancer followed by Her2Bi armed activated T cells (ATCs) may significantly improve the pathologic complete response (pCR) rate at the time of surgery. Arming ex vivo expanded T cells in the laboratory may help the T cells kill more tumor cells when they are put back in the body. Giving combination neoadjuvant chemotherapy followed by laboratory-treated T cells before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed. PURPOSE: This phase II clinical trial is studying how well giving laboratory-treated T cells after neoadjuvant chemotherapy works in treating women with stage II or stage III breast cancer undergoing surgery.

Breast Cancer

Barbara Ann Karmanos Cancer Institute8 participantsStarted Jul 2010

Detroit, Michigan, United States

A Study of BMS-863233 in Patients With Advanced and/or Metastatic Solid Tumors

Targeted T Cells After Neoadjuvant Chemotherapy in Treating Women With Stage II or III Breast Cancer Undergoing Surgery

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Surgery to Remove the Sentinel Lymph Node and Axillary Lymph Nodes After Chemotherapy in Treating Women With Stage II, Stage IIIA, or Stage IIIB Breast Cancer

Genomic Response Analysis of Heart Failure Therapy in African Americans

tPA by Endovascular Administration for the Treatment of Submassive PE Using CDT for the Reduction of Thrombus Burden

Ketorolac on Posterior Thoracolumbar Spinal Fusions

Efficacy, Safety, and Pharmacokinetics of APT-1011 in Subjects With Eosinophilic Esophagitis (EoE)

Cognitive Behavioral Suicide Prevention for Psychosis: Aim 1

Randomized Trial in Adult Participants With Acute Migraines

A Study Evaluating Intensive Chemotherapy With or Without Glasdegib or Azacitidine With or Without Glasdegib In Patients With Previously Untreated Acute Myeloid Leukemia

A Study to Evaluate the Safety and Efficacy of BIIB104 in Participants With Cognitive Impairment Associated With Schizophrenia (CIAS)

A Safety and Efficacy Study of XERMELO® + First-line Chemotherapy in Patients With Advanced Biliary Tract Cancer

A Study to Evaluate the Safety and Efficacy of VX-121 Combination Therapy in Subjects With Cystic Fibrosis

Video Gaming for Home Rehabilitation for Children With Hemiplegic Cerebral Palsy in Costa Rica

FX-322 in Adults With Stable Sensorineural Hearing Loss

Relative Bioavailability of LY03010 Compared to Listed Drug

A Study to Evaluate the Efficacy, Safety, and Tolerability of CBL-514 Injection for Reducing Subcutaneous Fat (Stage 2)

Rapid Diagnostics for HIV and Hepatitis

Evaluating the Safety and Immune Response to Three Different DNA HIV Vaccines Administered With a MVA-CMDR Boost Vaccine in Healthy, HIV-Uninfected Adults

A Study of TY-2136b in Patients With Advanced Solid Tumors Harboring ALK, ROS1 or NTRK1-3 Alterations