Clinical Trials in Detroit

Showing 6041-6060 of 19,719 trials

Safety & Immunogenicity of JNJ-64041757, Live-attenuated Double-deleted Listeria Immunotherapy, in Subjects With Non Small Cell Lung Cancer

NCT02592967

The purpose of this study is to determine the recommended Phase 2 dose (RP2D) of JNJ-64041757 a live attenuated double deleted (LADD) Listeria monocytogenes (bacteria in which two virulence genes, which encode molecules that help cause disease, have been removed) when administered intravenously to participants with advanced (Stage IIIb) or metastatic (Stage IV) NSCLC (adenocarcinoma).

Carcinoma, Non-Small-Cell Lung

Janssen Research & Development, LLC18 participantsStarted Dec 2015

Duarte, California, United States • Baltimore, Maryland, United States • Bethesda, Maryland, United States +6 more locations

TERMINATEDPhase 3< 1 mile

Pulmonary Rehabilitation Before Lung Cancer Resection

NCT02887521

This is a study funded by the National Institute of Health. The rationale for the need of this research is the lack of any well proven risk-reducing intervention that may decrease the morbidity of lung cancer resection in patients with COPD or that may improve their quality of life trajectory, a meaningful outcome in the overall disease progression. The proposed intervention is unique as it combines exercise and behavioral interventions that were pilot tested in a randomized single-blinded controlled design in the proposed population and proved feasible and potentially effective. The aim is to test the effect of the proposed rehabilitation on length of stay, pulmonary complications and quality of life trajectory.

Non-small Cell Lung Cancer (NSCLC)Chronic Obstructive Pulmonary Disease (COPD)

Alliance for Clinical Trials in Oncology9 participantsStarted Feb 2018

Jacksonville, Florida, United States • Chicago, Illinois, United States • Detroit, Michigan, United States +4 more locations

Safety & Immunogenicity of JNJ-64041757, Live-attenuated Double-deleted Listeria Immunotherapy, in Subjects With Non Small Cell Lung Cancer

Pulmonary Rehabilitation Before Lung Cancer Resection

Find Trials by Condition in Detroit

A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of JNJ-42756493 in Adult Participants With Advanced or Refractory Solid Tumors or Lymphoma

Avelumab in First-line NSCLC (JAVELIN Lung 100)

Real-World Study of Enzalutamide and Abiraterone Acetate (With Prednisone) Tolerability

The ShortCut™ Study Protocol

An Observational Study of Beta-Blocker Use in Patients With COPD and Acute MI

Nirogacestat for Adults With Desmoid Tumor/Aggressive Fibromatosis (DT/AF)

A Study on the Immune Response and Safety of an Adjuvanted Human Papillomavirus Vaccine When Given to Healthy Women 16 to 26 Years of Age

Self-management for People with Epilepsy

Spinal Cord Stimulation vs. Medical Management for Low Back Pain (DISTINCT)

A Study of Guselkumab in Participants With Familial Adenomatous Polyposis

Study of Angiogenic Cell Therapy for Progressive Pulmonary Hypertension

A Study of Acute Respiratory Infections in Global Outpatient Setting

A Study of Abiraterone Acetate Plus Low-Dose Prednisone Plus Androgen Deprivation Therapy (ADT) Versus ADT Alone in Newly Diagnosed Participants With High-Risk, Metastatic Hormone-Naive Prostate Cancer (mHNPC)

Efficacy and Safety of GWP42003-P Oral Solution in Children With Epilepsy With Myoclonic-atonic Seizures

A Study of mRNA-1011.1, mRNA-1011.2, and mRNA-1012.1 Candidate Seasonal Influenza Vaccines in Healthy Adults

Tailored Axillary Surgery With or Without Axillary Lymph Node Dissection Followed by Radiotherapy in Patients With Clinically Node-positive Breast Cancer (TAXIS)

Safety, Reactogenicity and Immunogenicity of Adenovirus Serotype 26 (Ad26)- and Modified Vaccinia Ankara (MVA)-Vectored Vaccine Components in Otherwise Healthy Women With HPV16 or HPV18 Infection of the Cervix

A Study of Subcutaneously-administered Guselkumab Delivered by 3 Different Devices in Healthy Participants