Clinical Trials in Detroit

Showing 5481-5500 of 19,719 trials

Study to Evaluate Safety and PK of CHS-006 in Combination With Toripalimab in Patients With Advanced Solid Tumors

NCT05757492

This phase 1 open-label study will evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary efficacy of CHS-006 in combination with toripalimab in 2 phases. Phase 1 (Dose Optimization phase) will explore 2 different dose combinations in participants with advanced/metastatic solid tumors (except pancreatic) and Phase 2 (Indication-specific Expansion phase) will use one selected dose in specific tumor types (non-small cell lung cancer-non squamous \[NSCLC-NS\] and Hepatocellular carcinoma \[HCC\])

Advanced Solid TumorNon-Small Cell Lung CancerHepatocellular Carcinoma

Coherus Oncology, Inc.22 participantsStarted Apr 2023

Orlando, Florida, United States • Detroit, Michigan, United States • Reno, Nevada, United States +1 more locations

COMPLETEDNA10 miles

Peer Mentorship to Reduce Suicide Attempts Among High-Risk Adults

NCT03373916

This is a single-blind, randomized controlled trial to test the effectiveness of a peer mentorship intervention (PREVAIL) for reducing suicide risk compared to enhanced usual care among participants (N=455) at high-risk for suicide recruited from inpatient psychiatric units.

Suicidal Ideation

University of Michigan455 participantsStarted Jun 2018

Ann Arbor, Michigan, United States • Ferndale, Michigan, United States • Mount Clemens, Michigan, United States

Study to Evaluate Safety and PK of CHS-006 in Combination With Toripalimab in Patients With Advanced Solid Tumors

Peer Mentorship to Reduce Suicide Attempts Among High-Risk Adults

Find Trials by Condition in Detroit

A Study to Evaluate the Safety and Efficacy of Ustekinumab Induction and Maintenance Therapy in Participants With Moderately to Severely Active Ulcerative Colitis

A Study of Encapsulated Cell Technology (ECT) Implant for Participants With Early Stage Retinitis Pigmentosa

A Study of Ustekinumab in Participants With Active Systemic Lupus Erythematosus

Derm-Maxx in Patients With Diabetic Foot Ulcers Unresponsive to Standard of Care Treatment Alone

A Study Comparing Daratumumab, Lenalidomide, and Dexamethasone With Lenalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma

Post Approval Study of Liposorber LA-15 System for the Treatment of Focal Segmental Glomerulosclerosis in Children

Obstructive Sleep Apnea Master Protocol GPIF: A Study of Tirzepatide (LY3298176) in Participants With Obstructive Sleep Apnea

ShOrt neCK AAA RAndomized Trial - ESAR and FEVAR: SOCRATES

The ENERGY 3 Study: Evaluation of Efficacy and Safety of INZ-701 in Children With ENPP1 Deficiency

Expanded Access for Cancer Treatment With Balstilimab (AGEN2034) and Zalifrelimab (AGEN1884)

Safety, Tolerability and Efficacy of ACZ885 on Leg Artery Structure in Patients With Peripheral Artery Disease

Zibotentan and Dapagliflozin in Patients With Type 2 Diabetes and Elevated Albuminuria

A Study to Evaluate the Safety and Efficacy of Intranasal Esketamine in Treatment-resistant Depression

A Study of Carfilzomib, Lenalidomide, Dexamethasone and Daratumumab for Patients With Relapsed/Refractory Myeloma With Salvage Autologous Hematopoietic Cell Transplantation

A Study to Evaluate the Efficacy and Safety of VIB4920 in Participants With Sjögren's Syndrome

Study of AGEN1571 in Participants With Advanced Solid Tumors

A Digital Intervention to Improve Physical Activity and Sleep Behaviors in Youth With Psychiatric Diagnoses

An Investigation to Validate Speech Perception Assessment for Adult Cochlear Recipients Using a Mobile Research App