Clinical Trials in Detroit

Showing 5181-5200 of 19,719 trials

Validation of a Multi-gene Test for Lung Cancer Risk

NCT01130285

The purpose of this study is to determine the validity of a multi-gene Lung Cancer Risk Test (LCRT). In the process, the investigators will establish a bank of NBEC samples and corresponding blood samples from individuals demographically at increased risk for lung cancer.

Lung Cancer

University of Toledo Health Science Campus403 participantsStarted May 2011

Denver, Colorado, United States • Ann Arbor, Michigan, United States • Detroit, Michigan, United States +10 more locations

RECRUITINGPhase 2< 1 mile

Isatuximab During Stem Cell Collection and Transplant in Patients With Multiple Myeloma and Lymphoma

NCT05346809

The purpose of this study is to see if Isatuximab can alter the immune system in patients with multiple myeloma or lymphoma upon recovery from the autologous stem cell transplantation. The investigators will see if Isatuximab makes changes to the immune system so that upon recovery from the transplant, the immune system can fight the cancer. This study will have two arms. On one arm (control arm), participants will receive standard transplant procedures and on the other arm (experimental arm), participants will receive Isatuximab in addition to the standard transplant procedures. The assignment to these arms is done randomly (determined by chance, like flipping a coin) by a computer. Each participant will have about 66% chance of getting on the experimental arm and about 33% chance of getting on the control arm.

LymphomaMultiple MyelomaNon-Hodgkin Lymphoma+1 more

Divaya Bhutani39 participantsStarted Mar 2023

Detroit, Michigan, United States • New York, New York, United States

Validation of a Multi-gene Test for Lung Cancer Risk

Isatuximab During Stem Cell Collection and Transplant in Patients With Multiple Myeloma and Lymphoma

Find Trials by Condition in Detroit

Study of Orally Administered AG-120 in Subjects With Advanced Hematologic Malignancies With an IDH1 Mutation

JAGUAR Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization

A 52-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough

Use of Consumer Sleep Technology to Treat Shift Work Disorder

Alzheimer's Plasma Extension

Tolerability of the Combination of Lapatinib and Trastuzumab in Adults Age 60 or Older With HER2 Positive Locally Advanced or Metastatic Breast Cancer

Trial of Newly Diagnosed High Grade Glioma Treated With Concurrent Radiation Therapy, Temozolomide and BMX-001

Study of the Efficacy and Safety PF-06741086 in Adult and Teenage Participants With Severe Hemophilia A or Moderately Severe to Severe Hemophilia B

Nemvaleukin Alfa Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Cutaneous or Mucosal Melanoma - ARTISTRY-6

TAC T-cells for the Treatment of HER2-positive Solid Tumors

Abraxane® With or Without Mifepristone for Advanced, Glucocorticoid Receptor-Positive, Triple-Negative Breast Cancer

A Study to Assess Safety and Target Engagement of E2814 in Participants With Mild to Moderate Cognitive Impairment Due to Dominantly Inherited Alzheimer's Disease

ProVIDE II Bridging Study

D-PLEX 312 - Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection (SHIELD II)

Understanding the Natural History Early in the Course or Presentation of Friedreich Ataxia

Study of Neoadjuvant Olaparib Monotherapy and Olaparib and Durvalumab Combination in HER2 Negative BRCAm Breast Cancer

ZZ06 in Adult Patients With Advanced Solid Tumor Malignancies

VB-111 in Surgically Accessible Recurrent/Progressive GBM