Clinical Trials in Detroit

Showing 3821-3840 of 19,719 trials

Selinexor, Carfilzomib, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma

NCT02199665

This phase I trial studies the side effects and best dose of selinexor and carfilzomib when given together with dexamethasone in treating patients with multiple myeloma that has returned or does not respond to treatment. Drugs used in chemotherapy, such as selinexor and dexamethasone, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Carfilzomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving selinexor, carfilzomib, and dexamethasone may be a better treatment for multiple myeloma.

Refractory Multiple Myeloma

University of Chicago52 participantsStarted Jun 2014

Scottsdale, Arizona, United States • Chicago, Illinois, United States • Ann Arbor, Michigan, United States +2 more locations

COMPLETEDNA< 1 mile

Enhancing Sexual Safety: Couples' Communication and HIV Testing Among YMSM

NCT04289116

The purpose of this study is to compare different ways to deliver the couples HIV Testing and Counseling (CHTC) intervention that is suited for adolescents and young adults.

HIV/AIDSHIV Infections

Florida State University71 participantsStarted Jan 2020

Detroit, Michigan, United States • New York, New York, United States

Selinexor, Carfilzomib, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma

Enhancing Sexual Safety: Couples' Communication and HIV Testing Among YMSM

Find Trials by Condition in Detroit

Pivotal, Open-label, Randomized Study of Radiosurgery With or Without Tumor Treating Fields (TTFields) for 1-10 Brain Metastases From Non-small Cell Lung Cancer (NSCLC).

Paclitaxel, Carboplatin, and Bevacizumab or Paclitaxel, Carboplatin, and Temsirolimus or Ixabepilone, Carboplatin, and Bevacizumab in Treating Patients With Stage III, Stage IV, or Recurrent Endometrial Cancer

A Phase 2a Proof-of-Concept Trial of Bempikibart (ADX-914) for the Treatment of Severe Alopecia Areata (SIGNAL-AA)

A Study to Describe the Characteristics, Health Care Interventions and Outcomes of Patients With Major Bleedings in the Presence of Factor Xa Inhibitor Treatment

Ertugliflozin Type 2 Diabetes Mellitus (T2DM) Pediatric Study (MK-8835/PF-04971729) (MK-8835-059)

Study to Assess the Efficacy & Safety of KHK4951 in Patients With Neovascular Age-Related Macular Degeneration

Metacognitive Self Control and Job Interview Training

Clinical Trial Evaluating ITI-007 (Lumateperone) as a Monotherapy for the Treatment of Bipolar Depression

To Evaluate Safety and Tolerability of the Fixed- Dose Combination of Obeticholic Acid and Bezafibrate

Combining a Smartphone App With Medications to Manage Heavy Drinking

A Real-world Long-term Safety and Immunogenicity Study of Olipudase Alfa Therapy in Pediatric Patients Less Than 2 Years of Age With Acid Sphingomyelinase Deficiency (ASMD)

Efficacy and Safety of Encaleret Compared to Standard of Care in Participants With ADH1

Multicenter Assessment of the Pancreas in Type 1 Diabetes

Post-Market Study to Assess iTind Safety in Comparison to UroLift

A Modular Phase 1/2 Study With CT7439 in Participants With Solid Malignancies

SARC044: A Phase II Trial of Bezuclastinib in Combination With Sunitinib in Patients With GIST

Cognitive Training and Neuroplasticity in Mild Cognitive Impairment: COGIT-2 Trial

Phase 3, Randomized, Placebo-Controlled Study of Tinlarebant to Explore Safety and Efficacy in Adolescent Stargardt Disease