Clinical Trials in Detroit

Showing 2881-2900 of 19,719 trials

A Phase I/II Study of Nivolumab, Ipilimumab and Plinabulin in Patients With Recurrent Small Cell Lung Cancer

NCT03575793

This is an open-label Phase I/II study, with a dose escalation part (Phase I) and a single-arm part (Phase II), in patients with recurrent SCLC who progressed after first-line platinum-based chemotherapy and who are candidates for second line therapy. No PK evaluation is planned in this study as nivolumab and ipilimumab are unlikely to alter plinabulin's PK, since the route of excretion is different.

Lung CancerSCLC

Salma Sabbour39 participantsStarted Sep 2018

Duarte, California, United States • Tampa, Florida, United States • Chicago, Illinois, United States +5 more locations

COMPLETEDPhase 2< 1 mile

A Study of Tiragolumab in Combination With Atezolizumab in Chemotherapy-Naïve Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

NCT03563716

This study will evaluate the safety and efficacy of tiragolumab plus atezolizumab compared with placebo plus atezolizumab in chemotherapy-naive patients with locally advanced unresectable or metastatic PD-L1-selected non-small cell lung cancer (NSCLC), excluding patients with a sensitizing EGFR mutation or ALK translocation.

Non-small Cell Lung Cancer

Genentech, Inc.135 participantsStarted Aug 2018

Tempe, Arizona, United States • Fort Myers, Florida, United States • St. Petersburg, Florida, United States +37 more locations

A Phase I/II Study of Nivolumab, Ipilimumab and Plinabulin in Patients With Recurrent Small Cell Lung Cancer

A Study of Tiragolumab in Combination With Atezolizumab in Chemotherapy-Naïve Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Find Trials by Condition in Detroit

Unresectable Stage IIIA/IIIB Non-small Cell Lung Cancer (NSCLC)

Capivasertib+Abiraterone as Treatment for Patients With Metastatic Hormone-sensitive Prostate Cancer and PTEN Deficiency

A Study to Assess the Efficacy and Safety of Risankizumab in Participants With Ulcerative Colitis

Mymobility Knee ROM

Self-Administered Relaxing Acupressure to Reduce Fatigue in Adolescent and Young Adult Cancer Survivors

Bioresorbable Airway Splint Pivotal Clinical Trial

A Study of Retatrutide (LY3437943) Once Weekly in Participants Who Have Obesity or Overweight and Osteoarthritis of the Knee

A Phase III Study to Assess the Effect of AZD0780 on LDL-C in Patients With Clinical ASCVD or at Risk for a First ASCVD Event

Clinical Trial of a Hydrophilic EMV Toric Lens RAO210T in the Correction of Aphakia and Corneal Astigmatism

A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer

A Study Comparing Daratumumab, VELCADE (Bortezomib), Lenalidomide, and Dexamethasone (D-VRd) With VELCADE, Lenalidomide, and Dexamethasone (VRd) in Participants With Untreated Multiple Myeloma and for Whom Hematopoietic Stem Cell Transplant is Not Planned as Initial Therapy

Assessment of GORE® SYNECOR Biomaterial in Focused Patient Populations and Long-Term Application

A Study to Determine if BHV-7000 is Effective and Safe in Adults With Idiopathic Generalized Epilepsy With Generalized Tonic-clonic Seizures

Expanded Access Protocol for Boys With Duchenne Muscular Dystrophy

EXoPERT EMERALD Clinical Study

Confirmatory Trial for Alleviating Fatigue in Multiple Sclerosis

The PediQUEST Response to Pain Of Children With Neurologic Disability Pilot Randomized Controlled Trial

A Phase IIb Study to Evaluate the Safety of Zibotentan/Dapagliflozin in Participants With Cirrhosis-ZEAL-UNLOCK