Clinical Trials in Denver

Showing 1941-1960 of 15,604 trials

RECRUITING< 1 mile

The Immune System's Response to Young Women's Breast Cancer

NCT01503190

This study plans to learn more about the immune system's response to breast cancer in young women.

Breast CancerBreast Cancer and Pregnancy

University of Colorado, Denver800 participantsStarted Jul 2009

Aurora, Colorado, United States • Denver, Colorado, United States • Denver, Colorado, United States +2 more locations

RECRUITINGPhase 1/2< 1 mile

Study of Ifinatamab Deruxtecan (DS-7300a, I-DXd) in Participants With Advanced Solid Malignant Tumors

NCT04145622

This is a single group study of participants with advanced solid tumors who have not been cured by other treatments. It is the first time the drug will be used in humans, and will be in two parts. The primary purpose of the parts are: * Dose Escalation Part: To evaluate the safety and tolerability and to determine the maximum tolerated dose and the recommended dose for expansion of ifinatamab deruxtecan (I-DXd). * Dose Expansion Part: To investigate the safety, tolerability and antitumor activity of I-DXd when administered as a single agent. This study is expected to last approximately 5 years from the time the first participant is enrolled to the time the last participant is off the study. The number of treatment cycles is not fixed in this study. Participants who continue to benefit from the study treatment may continue, unless: * they withdraw * their disease gets worse * they experience unacceptable side effects.

Advanced Solid TumorMalignant Solid Tumor

Daiichi Sankyo250 participantsStarted Nov 2019

Los Angeles, California, United States • Denver, Colorado, United States • Orlando, Florida, United States +22 more locations

The Immune System's Response to Young Women's Breast Cancer

Study of Ifinatamab Deruxtecan (DS-7300a, I-DXd) in Participants With Advanced Solid Malignant Tumors

Find Trials by Condition in Denver

Optimal Pediatric Heart Transplant Immunosuppression With MicroRNAs

Window of Opportunity Study Targeting the Inflammatory Milieu

Phase III Study Assessing the Efficacy and Safety of Pegcetacoplan in Patients With C3 Glomerulopathy or Immune-Complex Membranoproliferative Glomerulonephritis

Assessing an Oral EGFR Inhibitor, Sunvozertinib in Patients Who Have Advanced Non-small Cell Lung Cancer With EGFR or HER2 Mutation (WU-KONG1)

Bladder and Bone Effects of Pelvic Radiation Therapy in Childhood Cancer Survivors

A Study in Patients Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study

A Study to Evaluate the Efficacy and Safety of ABC008 for Inclusion Body Myositis

A Study of a Novel Iron-based Phosphate Binder AP301 in Patients With Hyperphosphatemia in the U.S. and China

Study to Compare Efficacy, Safety, and Immunogenicity of LUBT010 (Proposed Ranibizumab Biosimilar) and Lucentis® in Patients With Neovascular AMD

Home OCT-Guided Treatment Versus Treat and Extend for the Management of Neovascular AMD

Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System

Safety and Performance Using Legion™ CR Oxinium and CoCr Femoral Implants Combined With Legion™/Genesis™ II XLPE High Flex Tibial Inserts

R-3750 in Patients With Mild to Moderate Ulcerative Colitis

A Study With CIT-013 in HS Patients

A Study of PHN-010 in Patients With Advanced Solid Tumors

Pacritinib in Relapsed/Refractory T-cell Lymphoproliferative Neoplasms

A Study of HMPL-306 in Advanced Hematological Malignancies With mIDH

TACE With or Without SBRT as Bridging Therapy for Pre-transplant HCC Patients