Clinical Trials in Denver

Showing 11541-11560 of 15,604 trials

Dose Escalation Study of Gemcitabine and ON 01910.Na in Solid Tumors

NCT01125891

Treatment of cancer is often more effective when two or more drugs are used together. For example, when gemcitabine, an approved drug, and ON 01910.Na, a new investigational anti-cancer drug, are used together to treat cancer cells in laboratory animals, there is more inhibition of the growth of the cancer cells compared to either drug used by itself. These results offer promise that gemcitabine and ON 01910.Na could be used to treat cancer in patients. However, before studies that seek to find out if gemcitabine and ON 01910.Na is an effective combination in patients can be done, doctors must first know what is largest, safe dose of ON 01910.Na that can be used in combination with gemcitabine. This study is designed to answer that question.

Malignant NeoplasmasSolid Tumors

Traws Pharma, Inc.39 participantsStarted Jan 2009

Denver, Colorado, United States • Buffalo, New York, United States

TERMINATEDPhase 2< 1 mile

A Study of MM-111 and Paclitaxel With Trastuzumab in Patients HER2 Positive Carcinomas of the Distal Esophagus, Gastroesophageal (GE) Junction and Stomach

NCT01774851

To determine whether the combination of MM-111 plus paclitaxel and trastuzumab is more effective than paclitaxel and trastuzumab alone

HER-2 Gene AmplificationEsophagus CancerGastroesophageal Junction Cancer+1 more

Merrimack Pharmaceuticals84 participantsStarted Jan 2013

Birmingham, Alabama, United States • Los Angeles, California, United States • Los Angeles, California, United States +18 more locations

Dose Escalation Study of Gemcitabine and ON 01910.Na in Solid Tumors

A Study of MM-111 and Paclitaxel With Trastuzumab in Patients HER2 Positive Carcinomas of the Distal Esophagus, Gastroesophageal (GE) Junction and Stomach

Find Trials by Condition in Denver

Inhaled Corticosteroid Replacement Study - Efficacy and Safety of Ro 27-2441 (Test Drug) in Moderate Persistent Asthma

S0800, Nab-Paclitaxel, Doxorubicin, Cyclophosphamide, and Pegfilgrastim With or Without Bevacizumab in Treating Women With Inflammatory or Locally Advanced Breast Cancer

Platinum-based Chemoradiotherapy and Rigosertib in Head and Neck Cancer

To Evaluate Sarilumab - SAR153191 (REGN88) - Auto-injector Device In Patients With Rheumatoid Arthritis

To Evaluate The Safety of SAR153191 (REGN88) and Tocilizumab Added to Other RA Drugs in Patients With RA Who Are Not Responding to or Intolerant of Anti-TNF Therapy (SARIL-RA-ASCERTAIN)

Trial of Linaclotide in Patients With Chronic Idiopathic Constipation

To Evaluate the Immunogenicity and Safety of Sarilumab Administered as Monotherapy in Patients With Rheumatoid Arthritis (RA)

A Study of Intravenous Thrombolysis With Alteplase in MRI-Selected Patients

A Study of Bevacizumab in Combination With Capecitabine and Cisplatin as First-line Therapy in Patients With Advanced Gastric Cancer

Hyper- and Hypokalemic Periodic Paralysis Study

Efficacy and Safety of Oral Rigosertib in Transfusion-dependent, Low or Int-1 or Trisomy 8 Int-2 Myelodysplastic Syndrome

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK1362885 in Type 2 Diabetics

Impact of SBI, a Medical Food, on Nutritional Status in Patients With HIV-associated Enteropathy

A 48 Week Study Comparing Treatment With Saquinavir + Lopinavir/Ritonavir in Combination With Enfuvirtide HAART Versus Saquinavir + Lopinavir/Ritonavir + Other Nucleoside Combinations to See the Efficacy of These Treatments in Patients Infected With HIV-1

Study of Tissue Samples From Patients With Non-Small Cell Lung Cancer

A Study To Evaluate The Safety Of Voriconazole As Treatment Of Invasive Aspergillosis (Fungal Infection) And Other Rare Molds In Children

Long-Term Extension Study of Ofatumumab in Subjects With Pemphigus Vulgaris

Evaluating Processes of Care & the Outcomes of Children in Hospital (EPOCH)