Clinical Trials in Denver

Showing 8721-8740 of 18,161 trials

Deceased Organ Donor Interventions to Protect Kidney Graft Function

NCT02525510

To protect kidney function during the transplantation process by comparing mild hypothermia in the deceased organ donor before organs are recovered and pulsatile perfusion of the kidney after recovery and prior to transplantation.

Brain DeathOrgan DonationOrgan Transplant Failure or Rejection+1 more

University of California, San Francisco1,427 participantsStarted Jul 2017

Phoenix, Arizona, United States • San Francisco, California, United States • Denver, Colorado, United States +4 more locations

TERMINATEDPhase 3< 1 mile

Evaluation of the Efficacy and Safety of Sarilumab in Patients With Polymyalgia Rheumatica

NCT03600818

Primary Objective: To evaluate the efficacy of KEVZARA (sarilumab) in participants with polymyalgia rheumatica (PMR) as assessed by the proportion of participants with sustained remission for sarilumab with a shorter corticosteroid (CS) tapering regimen as compared to placebo with a longer CS tapering regimen. Secondary Objectives: * To demonstrate the efficacy of sarilumab in participants with PMR compared to placebo, in combination with a CS taper with regards to: * Clinical responses (such as components of sustained remission, disease remission rates, time to first disease flare) over time. * Cumulative CS (including prednisone) exposure. * To assess the safety (including immunogenicity) and tolerability of sarilumab in participants with PMR. * To measure sarilumab serum concentrations in participants with PMR. * To assess the effect of sarilumab in reducing glucocorticoid toxicity as measured by the composite glucocorticoid toxicity index (GTI) questionnaire.

Polymyalgia Rheumatica

Sanofi118 participantsStarted Oct 2018

Upland, California, United States • Denver, Colorado, United States • Stamford, Connecticut, United States +81 more locations

Deceased Organ Donor Interventions to Protect Kidney Graft Function

Evaluation of the Efficacy and Safety of Sarilumab in Patients With Polymyalgia Rheumatica

Find Trials by Condition in Denver

Radiation Therapy in Treating Patients With Prostate Cancer

Study of Efficacy, Safety, Tolerability, Pharmacokinetic (PK) and Pharmacodynamic (PD) of an Anti-CD40 Monoclonal Antibody, CFZ533, in Kidney Transplant Recipients

A Study to Assess the Effectiveness of the Nautilus BrainPulse™ as an Aid in the Diagnosis of Concussion

Study of the Safety and Efficacy of Elagolix in Women With Polycystic Ovary Syndrome

N-Force Screws Augmented With N-Force Blue in Hip Fractures

Term Infants Fed a Partially Hydrolyzed Whey Protein-Based Formula

Avelumab in First-Line Maintenance Gastric Cancer (JAVELIN Gastric 100)

Percutaneous Endovascular Aneurysm Repair (PEVAR) Trial

Efficacy, Safety, and Pharmacokinetic Profiles of REGN3500 Administered to Adult Patients With Moderate-to-Severe Atopic Dermatitis

Dapagliflozin in Respiratory Failure in Patients With COVID-19

OCT Reference Database

Pazopanib Hydrochloride and Topotecan Hydrochloride in Treating Patients With Metastatic Soft Tissue and Bone Sarcomas

Triton Reference Database

A Study of LJPC-401 for the Treatment of Iron Overload in Adult Patients With Hereditary Hemochromatosis

Long-term Follow-up Study of Allogeneic Gamma Delta (γδ) CAR T Cells

International BPA Registry

Clinical Validation of New OCT System

Study To Assess A Radiofrequency Microneedling Device For Dermatologic Conditions