Clinical Trials in Denver

Showing 761-780 of 8,669 trials

Quantification of Phosphorylated Alpha-synuclein in Cutaneous Biopsies as a Prospective Biomarker in Parkinson's Disease

NCT06621602

This study aims to assess the levels of phosphorylated alpha-synuclein (P-SYN) in patients with Parkinson's disease and REM Behavior Disorder using a minimally invasive skin punch biopsy. It seeks to understand the natural progression of P-SYN deposition over time to explore the potential of P-SYN quantification as a biomarker for disease progression.

REM Behavior DisorderParkinson Disease

CND Life Sciences100 participantsStarted Dec 2024

Scottsdale, Arizona, United States • Scottsdale, Arizona, United States • Aliso Viejo, California, United States +15 more locations

COMPLETEDPHASE2/PHASE38.4 miles

Efficacy and Safety of Clesrovimab (MK-1654) in Infants (MK-1654-004)

NCT04767373

The primary objectives of this phase 2b/3 double-blind, randomized, placebo-controlled study are to evaluate the efficacy and safety of clesrovimab in healthy pre-term and full-term infants. It is hypothesized that clesrovimab will reduce the incidence of respiratory syncytial virus (RSV)-associated medically attended lower respiratory infection (MALRI) from Days 1 through 150 postdose compared to placebo.

Respiratory Syncytial Virus Infection

Merck Sharp & Dohme LLC3,632 participantsStarted Apr 2021

Dothan, Alabama, United States • Fayetteville, Arkansas, United States • Jonesboro, Arkansas, United States +214 more locations

Quantification of Phosphorylated Alpha-synuclein in Cutaneous Biopsies as a Prospective Biomarker in Parkinson's Disease

Efficacy and Safety of Clesrovimab (MK-1654) in Infants (MK-1654-004)

Find Trials by Condition in Denver

Amplatzer Amulet LAAO vs. NOAC

A Study of Navenibart in Participants With Hereditary Angioedema

Study of Single Agent Belantamab Mafodotin Versus Pomalidomide Plus Low-dose Dexamethasone (Pom/Dex) in Participants With Relapsed/Refractory Multiple Myeloma (RRMM)

A Randomized Trial to Evaluate Sequential vs Simultaneous Patching

A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years

A Study to Learn About BNT162b2 (LP.8.1)-Adapted Vaccine Against SARS-CoV-2 in Children 5 Through 11 Years of Age That Are Considered at Higher Risk of Severe COVID-19

Study of Natriuretic Peptide Receptor 1 (NPR1) Antagonist in Adult Patients With Postural Orthostatic Tachycardia Syndrome (POTS)

A Study of Barzolvolimab in Patients With Atopic Dermatitis

Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age

Study of Lunsekimig (SAR443765) Compared With Placebo in Adults With High-risk Asthma

The Golazo® Peripheral Atherectomy System for a Safe and Effective Atherectomy (GREAT Trial)

Intratumoral PH-762 for Cutaneous Carcinoma

Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment (MCI), or Have Mild-to-Moderate AD Dementia

A Study of AZD0120 in Autoimmune Diseases

Galleri® in the Medicare Population.

Osimertinib Plus Savolitinib in EGFRm+/MET+ NSCLC Following Prior Osimertinib

Safety And Efficacy Study Of Intravenous (IV) Administration Of Elezanumab To Assess Change In Upper Extremity Motor Score (UEMS) In Adult Participants With Acute Traumatic Cervical Spinal Cord Injury (SCI)

FdCyd and THU for Advanced Solid Tumors