Clinical Trials in Denver

Showing 7341-7360 of 13,773 trials

Biobanking of Rett Syndrome and Related Disorders

NCT02705677

The overarching purpose of this study is to advance understanding of the natural history of Rett syndrome (RTT), MECP2-duplication disorder (MECP2 Dup), RTT-related disorders including CDKL5, FOXG1, and individuals with MECP2 mutations who do not have RTT. Although all these disorders are the result of specific genetic changes, there remains broad clinical variation that is not entirely accounted for by known biological factors. Additionally, clinical investigators currently do not have any biomarkers of disease status, clinical severity, or responsiveness to therapeutic intervention. To address these issues, biological materials (DNA, RNA, plasma, cell lines) will be collected from affected individuals and in some cases from unaffected family members, initial evaluation performed to identify additional biological factors contributing to disease severity, and these materials will be stored for future characterization.

Rett SyndromeMECP2 DuplicationCDKL5+1 more

University of Alabama at Birmingham752 participantsStarted Sep 2017

Birmingham, Alabama, United States • Oakland, California, United States • San Diego, California, United States +9 more locations

COMPLETEDPhase 1< 1 mile

A Study of LY3295668 Erbumine in Participants With Extensive-stage Small-Cell Lung Cancer

NCT03898791

The purpose of this study is to determine the recommended phase 2 dose of LY3295668 erbumine in participants with platinum-sensitive, extensive-stage small-cell lung cancer.

Small Cell Lung Cancer

Eli Lilly and Company48 participantsStarted Jul 2019

Fayetteville, Arkansas, United States • Denver, Colorado, United States • Tampa, Florida, United States +37 more locations

Biobanking of Rett Syndrome and Related Disorders

A Study of LY3295668 Erbumine in Participants With Extensive-stage Small-Cell Lung Cancer

Find Trials by Condition in Denver

Natural History of Rett Syndrome & Related Disorders

Tesetaxel Plus Reduced Dose of Capecitabine in Patients With HER2 Negative, HR Positive, LA/MBC

Telmisartan to Reduce AIDS-Related Fibrotic and Inflammatory Contributors (TRAFIC Study)

Open Label, Phase III Study of NABI-IGIV 10% [Immune Globulin Intravenous(Human), 10%] In Subjects With Primary Immune Deficiency Disorders (PIDD)

A Study of Rovalpituzumab Tesirine as Maintenance Therapy Following First- Line Platinum-Based Chemotherapy in Participants With Extensive Stage Small Cell Lung Cancer (MERU)

A Study To Investigate Tanezumab In Patients With Interstitial Cystitis/ Painful Bladder Syndrome

Safety, Tolerability, PK, and Analgesic Effect of INL-001 in Children Following Open Inguinal Hernia Repair

A Study Investigating the Efficacy and Safety of Upadacitinib (ABT-494) Given With Methotrexate (MTX) in Adults With Rheumatoid Arthritis Who Have Had an Inadequate Response to MTX Alone

Varlitinib in Combination With Capecitabine for Advanced or Metastatic Biliary Tract Cancer

Safety and Efficacy of Sirolimus for HIV Reservoir Reduction in Individuals on Suppressive Antiretroviral Therapy (ART)

Systemic Chemotherapy and Subtenon Carboplatin, and Local Ophthalmic Therapy in Children With Intraocular Retinoblastoma

Study to Test the Safety, Tolerability and Efficacy of UCB7665 in Subjects With Moderate to Severe Myasthenia Gravis

Docetaxel and Carboplatin for Patients With mCRPC and DNA-Repair Deficiencies

Maraviroc to Augment Rehabilitation Outcomes After Stroke

A Phase 1/2 Multicenter Dose Escalation and Expansion Study Of NKTR-214 In Subjects With Locally Advanced Or Metastatic Solid Tumors

Preventing Excessive Gestational Weight Gain in Obese Women

Role of Rehabilitation in Concussion Management: A Randomized Controlled Trial

A Study With LJPC-401 for the Treatment of Myocardial Iron Overload in Patients With Transfusion-Dependent Beta Thalassemia