Clinical Trials in Denver

Showing 6941-6960 of 13,773 trials

Drug-Drug Interaction Study of Entinostat and Exemestane in Postmenopausal Women With ER+ Breast Cancer

NCT02820961

The purpose of this study is to determine the effect of exemestane on the pharmacokinetics (PK) of entinostat and to determine the effect of entinostat on the PK of exemestane in patients with locally recurrent or metastatic estrogen receptor positive (ER+) breast cancer. Additionally, this study will evaluate the safety and tolerability of entinostat in combination with exemestane, and assess the effectiveness of entinostat in combination with exemestane in terms of best overall response and overall survival.

Breast CancerEstrogen Receptor Positive Breast Cancer

Syndax Pharmaceuticals61 participantsStarted Jun 2016

Denver, Colorado, United States • Sarasota, Florida, United States • Nashville, Tennessee, United States

COMPLETEDPhase 3< 1 mile

Stem Cell Transplant With Lenalidomide Maintenance in Patients With Multiple Myeloma (BMT CTN 0702)

NCT01109004

The study is designed as a Phase III, multicenter trial of tandem autologous transplants plus maintenance therapy versus the strategy of single autologous transplant plus consolidation therapy with lenalidomide, bortezomib and dexamethasone (RVD) followed by maintenance therapy or single autologous transplant plus maintenance therapy as part of upfront treatment of multiple myeloma (MM). Lenalidomide will be used as maintenance therapy for three years in all arms.

Multiple Myeloma

National Heart, Lung, and Blood Institute (NHLBI)758 participantsStarted May 2010

Tucson, Arizona, United States • Duarte, California, United States • La Jolla, California, United States +51 more locations

Drug-Drug Interaction Study of Entinostat and Exemestane in Postmenopausal Women With ER+ Breast Cancer

Stem Cell Transplant With Lenalidomide Maintenance in Patients With Multiple Myeloma (BMT CTN 0702)

Find Trials by Condition in Denver

The Safety, Pharmacokinetics and Antitumor Activity of BGB-A317 in Combination With BGB-290 in Participants With Advanced Solid Tumors

Simvastatin to Prevent SCI-Induced Bone Loss

A Study of Obinutuzumab in Combination With Idasanutlin and Venetoclax in Participants With Relapsed or Refractory (R/R) Follicular Lymphoma (FL) or Rituximab in Combination With Idasanutlin and Venetoclax in Participants With R/R Diffuse Large B-Cell Lymphoma (DLBCL)

A Study of OKI-179 in Patients With Solid Tumors

Assessment of LBR-101 In Chronic Migraine

A Study of Flexible Dose Brexpiprazole as Monotherapy or Combination Therapy in the Treatment of Adults With Post-traumatic Stress Disorder (PTSD)

Long Term Safety and Efficacy Trial of Beclomethasone Dipropionate - Hydrofluoroalkane (BDP-HFA) 320 mcg in Allergic Rhinitis

Randomized Endo-Vein Graft Prospective

Study of INCB053914 in Subjects With Advanced Malignancies

HostDx Sepsis in the Diagnosis and Prognosis of Emergency Department Patients With Suspected Infections: a Multicenter Pilot Study

A Phase 1 Study of Nivolumab (BMS-936558) in Subjects With Advanced or Recurrent Malignancies

Restore EF Observational Study

Phase 2 Efficacy, Safety, and Tolerability Study of Natalizumab in Focal Epilepsy

A Study of Gantenerumab in Participants With Prodromal Alzheimer's Disease

PREMOD2 With Near Infrared Spectroscopy Sub-study

Comparison of Two Bronchodilator Inhalers in Pediatric Asthmatics

Study of CAD-9303 in Subjects With Schizophrenia

A Study to Evaluate Ovarian Follicular Activity and Hormone Levels for DR-102 Compared to Two 28-Day Oral Contraceptives