Clinical Trials in Denver

Showing 5921-5940 of 13,773 trials

First-line Pomalidomide, Bortezomib, and Dexamethasone For AL Amyloidosis or LCDD

NCT01728259

This phase I trial studies the side effects and best dose of pomalidomide and bortezomib when given together with dexamethasone in treating patients with amyloid light-chain amyloidosis or light chain deposition disease. Biological therapies, such as pomalidomide, may stimulate the immune system in different ways and stop abnormal cells from growing. Bortezomib may stop the growth of abnormal cells by blocking some of the enzymes needed for cell growth. Giving pomalidomide and bortezomib together with dexamethasone may be an effective treatment for amyloid light-chain amyloidosis or light chain deposition disease

Light Chain Deposition DiseasePrimary Systemic Amyloidosis

Barbara Ann Karmanos Cancer Institute18 participantsStarted Mar 2013

Denver, Colorado, United States • Boston, Massachusetts, United States • Detroit, Michigan, United States +2 more locations

TERMINATEDPhase 18.4 miles

Study of ABT-199 (GDC-0199) in Combination With Azacitidine or Decitabine (Chemo Combo) in Subjects With Acute Myelogenous Leukemia (AML)

NCT02203773

This is a Phase 1b, open-label, non-randomized, multicenter study to evaluate the safety and pharmacokinetics of orally administered venetoclax (ABT-199) combined with decitabine or azacitidine and the preliminary efficacy of these combinations. In addition, there is a drug-drug interaction (DDI) sub-study only at a single site, to assess the pharmacokinetics and safety of venetoclax (ABT-199) in combination with posaconazole.

Acute Myelogenous LeukemiaMyelogenous LeukemiaTreatment Naive AML

AbbVie212 participantsStarted Oct 2014

Duarte, California, United States • Sacramento, California, United States • Aurora, Colorado, United States +20 more locations

First-line Pomalidomide, Bortezomib, and Dexamethasone For AL Amyloidosis or LCDD

Study of ABT-199 (GDC-0199) in Combination With Azacitidine or Decitabine (Chemo Combo) in Subjects With Acute Myelogenous Leukemia (AML)

Find Trials by Condition in Denver

Observational Study of Actigraphy in Pediatric Pulmonary Arterial Hypertension

Evaluating Adrenal Insufficiency in Adults With Eosinophilic Esophagitis on Chronic Swallowed Topical Steroids

P3 Long Term Safety Study of Once Daily SB204 in Acne

Study to Evaluate the Efficacy and Safety of Remdesivir in Participants With Severely Reduced Kidney Function Who Are Hospitalized for Coronavirus Disease 2019 (COVID-19)

ELUVIA™ Drug-eluting Stent Versus Zilver® PTX® Stent

rhBMP-2/CRM/CD HORIZON® Spinal System Pivotal Study

PK/PD and Long Term Safety Study of Benralizumab in Children With Severe Eosinophilic Asthma

Safety, Tolerability, and Pharmacodynamics of NOV-001 in Adult Subjects

Clinical Trial Evaluating ITI-007 as an Adjunctive Therapy to Lithium or Valproate for the Treatment of Bipolar Depression

Safety, Tolerability, and Exploratory Efficacy of Adjunctive EQU-001 for Seizures in Adults With Epilepsy

HBV-HIV Coinfection Research Network

Glycemic Control and the Brain in Children With Type 1 Diabetes

Promoting The Self-Regulation Of Energy Intake

First-in-human Study of CCW702 in Patients With Metastatic Castration Resistant Prostate Cancer

Trial of pIL-12 Electroporation in Squamous Cell Carcinoma of the Head and Neck (IL12HNSCC)

RISE Adult Medication Study

Study Evaluating the Efficacy and Safety of Yoni.Fit in Women With Stress Urinary Incontinence

Fiber to Reduce Colon Cancer in Alaska Native People