Clinical Trials in Denver

Showing 2241-2260 of 8,669 trials

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of ADCT-901 in Participants With Selected Advanced Solid Tumors

NCT04972981

The primary objectives of this study are to identify the recommended phase 2 dose (RP2D) and/or maximum tolerated dose (MTD), and to characterize the safety and the tolerability of ADCT-901.

Advanced Solid Tumors

ADC Therapeutics S.A.30 participantsStarted Sep 2021

Denver, Colorado, United States • New Haven, Connecticut, United States • Atlanta, Georgia, United States +10 more locations

Enrolling By Invitation< 1 mile

Mycobacteriophage Treatment of Non-tuberculosis Mycobacteria

NCT06262282

About 10 people with cystic fibrosis (CF) and persistent Nontuberculosis mycobacteria (NTM) infection despite treatment will be screened to find out if their NTM infection has at least one mycobacteriophage that is effective in killing the mycobacteria. Individuals who are found to have at least one phage will be offered assistance in pursuing FDA approval for treatment via expanded-access Individual New Drug (IND) for compassionate-use. They will receive phage treatment for 1 year along with their guideline-based antibiotics for NTM. Individuals who are not identified as having a phage match will be followed as they continue to receive guideline based antibiotic therapy for 1 year. All subjects, including those who do not have a phage match will continue to be observed for the duration of the study, or about 1 year.

Cystic FibrosisNontuberculous Mycobacterial Lung DiseaseNontuberculous Mycobacterium Infection+2 more

National Jewish Health10 participantsStarted Feb 2024

Birmingham, Alabama, United States • Los Angeles, California, United States • San Diego, California, United States +15 more locations

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of ADCT-901 in Participants With Selected Advanced Solid Tumors

Mycobacteriophage Treatment of Non-tuberculosis Mycobacteria

Find Trials by Condition in Denver

Rucaparib in Treating Patients With Genomic LOH High and/or Deleterious BRCA1/2 Mutation Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)

Parkinson's Foundation PD GENEration Genetic Registry

Safety, Tolerability and Acceptability of Long-Acting Cabotegravir (CAB LA) for the Prevention of HIV Among Adolescent Males

Cerebral Palsy Adult Transition Longitudinal Study

A Study of the Drugs AGN-242428 and AGN-231868 in Participants With Dry Eye Disease

Study of Nalbuphine HCl ER Tablets in Hemodialysis Patients With Uremic Pruritus

Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)

Apixaban in Preventing Secondary Cancer Related Venous Thrombosis in Cancer Patients Who Have Completed Anticoagulation Therapy

Early Treatment of Language Impairment in Young Children With Autism Spectrum Disorder With Leucovorin Calcium

Study to Assess the Immune Response, the Safety and the Reactogenicity of Respiratory Syncytial Virus (RSV) Prefusion Protein 3 Older Adult (OA) (RSVPreF3 OA) Investigational Vaccine When co Administered With PCV20 in Older Adults

An Efficacy and Safety Study of AG-221 (CC-90007) Versus Conventional Care Regimens in Older Subjects With Late Stage Acute Myeloid Leukemia Harboring an Isocitrate Dehydrogenase 2 Mutation

Study of Safety, Tolerability and Efficacy of PBGM01 in Pediatric Participants With GM1 Gangliosidosis

Efficacy & Safety of rAd-IFN Administered With Celecoxib & Gemcitabine in Patients With Malignant Pleural Mesothelioma

Stopping Aminosalicylate Therapy in Inactive Crohn's Disease

Safety and Efficacy Study of CFI-402411 in Subjects With Advanced Solid Malignancies

StimRouter Registry Clinical Protocol

A Phase 2 Study of the Safety and Efficacy of Brepocitinib in Adults With Cutaneous Sarcoidosis (BEACON)

PRimary Care Opioid Use Disorders Treatment (PROUD) Trial