Clinical Trials in Dallas

Showing 17281-17300 of 17,468 trials

Safety and Efficacy Study of MM-093 in Patients With Chronic Plaque Psoriasis

NCT00147329

Merrimack is conducting a research study to see if an experimental drug, called MM-093, is safe and effective in the treatment of psoriasis. MM-093 is a genetically engineered version of a naturally occurring protein called alpha fetoprotein (AFP). Adults normally have very small amounts of AFP in their bloodstream. However, during pregnancy, AFP levels in both the mother and the fetus are much higher than normal. It has been observed that some women with psoriasis and other autoimmune diseases such as rheumatoid arthritis have fewer symptoms during pregnancy, particularly during the third trimester. At this time, the levels of AFP in the blood of the mother and fetus are the highest. This observation led Merrimack to begin examining MM-093 as a potential treatment for psoriasis. This study is designed to further test the safety and effectiveness of MM-093 in patients with psoriasis.

Psoriasis

Merrimack Pharmaceuticals30 participantsStarted Sep 2005

Dallas, Texas, United States • Salt Lake City, Utah, United States

COMPLETEDPhase 2< 1 mile

Amonafide in Combination With Cytarabine in Secondary AML

NCT00273884

This protocol is designed to assess the safety and efficacy of amonafide in combination with cytarabine in subjects with previously untreated secondary AML.

Acute Myeloid Leukemia

Xanthus Pharmaceuticals, Inc.80 participantsStarted Aug 2005

Birmingham, Alabama, United States • Duarte, California, United States • Los Angeles, California, United States +18 more locations

Safety and Efficacy Study of MM-093 in Patients With Chronic Plaque Psoriasis

Amonafide in Combination With Cytarabine in Secondary AML

Find Trials by Condition in Dallas

Six Month Clinical Trial Assessing Efficacy And Safety Of Inhaled Insulin In Type 2 Diabetes

Efficacy of Dapsone as a Steroid Sparing Agent in Pemphigus Vulgaris

Cardiovascular Outcomes in the VA's Rheumatoid Arthritis(VARA) Population

A Study of Pemetrexed in Small Cell Lung Cancer, Which Has Returned

Evaluation of Intravenous Levosimendan Efficacy in the Short Term Treatment of Decompensated Chronic Heart Failure.

Safety and Immunogenicity of Recombinant DNA and Adenovirus Expressing L523S Protein in Early Stage Non-Small Cell Lung Cancer

Study Evaluating Mylotarg (Gemtuzumab Ozogamicin) in Usual Care

Study Evaluating the Safety & Efficacy of DVS-223 SR for Relief of Vasomotor Symptoms Associated With Menopause

Autologous T Cell Immunotherapy for Chronic Lymphocytic Leukemia (CLL) Patients

A Phase 2, Randomized, Open-Label Study Of Single Agent CI-1033 In Patients With Advanced Non-Small Cell Lung Cancer

ZP120 Add-on to Furosemide in Treatment of Acute or Sub-Acute Decompensated Heart Failure

To Evaluate the Long-Term Safety of Pregabalin in Refractory Partial Epilepsy.

Study of Safety in Hemolytic Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients Treated With Eculizumab

T Cell Immunotherapy for Multiple Myeloma Patients Undergoing a Bone Marrow Transplant

HepeX-B in Post Hepatic Allografts for Treatment of End Stage Liver Disease Due to Hepatitis B Infection

UT-15C SR in the Treatment of Critical Limb Ischemia

Effectiveness of Duloxetine in the Treatment of Stress Urinary Incontinence(Uncontrolled Leakage of Urine)

Bipolar Depression Study: Bipolar Depression Assessment Study on Treatment Response