Clinical Trials in Dallas

Showing 201-220 of 17,468 trials

Neurocognitive Decline in Patients With Brain Metastases

NCT03508752

The phase I component of the study is to identify maximal tolerated dose (MTD). The phase II is to evaluate neurocognitive decline.

Brain Metastases

University of Texas Southwestern Medical Center80 participantsStarted Dec 2017

Dallas, Texas, United States

RECRUITINGPhase 2< 1 mile

A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

NCT06680830

The goal of this Phase 2 clinical trial is to investigate the efficacy and safety of NEU-411 in men and women aged 40-80 years with early Parkinson's Disease (PD) who have predicted elevations in the activity of the "leucine-rich repeat kinase 2" ("LRRK2" for short) pathway based on their genetic profile. A DNA test will be used to identify the "LRRK2-driven" population with predicted elevation in the LRRK2 pathway.

Parkinson DiseaseParkinsonIdiopathic Parkinson Disease+2 more

Neuron23 Inc.150 participantsStarted Jan 2025

Sun City, Arizona, United States • Little Rock, Arkansas, United States • Fresno, California, United States +67 more locations

Neurocognitive Decline in Patients With Brain Metastases

A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

Find Trials by Condition in Dallas

A Study of AL102 in Patients With Progressing Desmoid Tumors

A Study to Assess Safety and Effectiveness of Elafibranor in Adult Participants With Primary Sclerosing Cholangitis.

A Study to Evaluate the Long-term Safety, Tolerability, and Efficacy of Subcutaneous Sonelokimab in Participants With Moderate to Severe Hidradenitis Suppurativa

Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)

Catheter-Related Early Thromboprophylaxis With Enoxaparin Studies

A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer

Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia

Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure

A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Systemic Lupus Erythematosus

A Randomized Comparison of Personalized Therapy Mgmt Based On Coronary Atherosclerotic Plaque Vs. Usual Care for Symptomatic Patients With Suspicion of CAD

A Study of Orelabrutinib in Patients With Secondary Progressive Multiple Sclerosis

A Clinical Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-011)

A Study of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-invasive Bladder Cancer (MIBC) of the Bladder

Telerehabilitation In The Home After Stroke

Dose-Escalation Study of HTX-034 Following Bunionectomy

Evaluation of Treatment Satisfaction and Preference for Sumavel DosePro in the Treatment of Migraine

A Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis Spasticity

Study to Evaluate Xtresse Serum in Individuals With Thinning Hair