Clinical Trials in Colorado

Showing 3541-3560 of 8,657 trials

Study of OT-101 in Treating Myopia

NCT04770610

This is a phase III, randomized, double-masked, placebo-controlled, parallel-group, multicenter safety, tolerability, and efficacy study of atropine sulfate 0.01% (OT-101) as an investigational treatment for myopia in pediatric subjects

Myopia, Progressive

Ocumension (Hong Kong) Limited678 participantsStarted Apr 2021

Colorado Springs, Colorado, United States • Fort Collins, Colorado, United States • Gainesville, Florida, United States +12 more locations

COMPLETEDPhase 148 miles

ADVM-022 Intravitreal Gene Therapy for Wet AMD

NCT03748784

ADVM-022 (AAV.7m8-aflibercept) is a gene therapy product developed for the treatment of neovascular (wet) age-related macular degeneration (wet AMD). Wet AMD is a serious condition and the leading cause of blindness in the elderly. The available therapies for treating wet AMD require life-long intravitreal (IVT) injections every 4-12 weeks to maintain efficacy. A one-time IVT administration of ADVM-022 has the potential to treat wet AMD by providing durable expression of therapeutic levels of intraocular anti-VEGF protein (aflibercept) and maintaining the vision of patients. ADVM-022 is designed to reduce the current treatment burden which often results in undertreatment and vision loss in patients with wet AMD receiving anti-VEGF therapy in clinical practice.

Adverum Biotechnologies, Inc.30 participantsStarted Nov 2018

Bakersfield, California, United States • Beverly Hills, California, United States • Golden, Colorado, United States +8 more locations

Study of OT-101 in Treating Myopia

ADVM-022 Intravitreal Gene Therapy for Wet AMD

Find Trials by Condition in Colorado

A Study of FT-7051 in Men With MCRPC

Look AHEAD: Action for Health in Diabetes

Enapotamab Vedotin (HuMax-AXL-ADC) Safety Study in Patients With Solid Tumors

DNA Methylation and Cancer Prevention: Duration and Intensity of Exercise

A Study of PRN1008 in Patients With Pemphigus

A Study to Evaluate Safety and Immunogenicity of One or Two Booster Vaccinations With H5N6 Influenza Vaccine in Adults Primed With H5N1 Influenza Vaccine or Unprimed

Coolief Cooled Radiofrequency vs. Conventional Radiofrequency to Manage OA Knee Pain

Evaluation of Intubation Conditions Following BX1000 or Rocuronium in Subjects Undergoing Surgery

Long-Chain Fatty Acid Oxidation Disorders (LC-FAOD) Extension Study for Subjects Previously Enrolled in Triheptanoin Studies

A Clinical Study of Cobimetinib Administered in Combination With Niraparib, With or Without Atezolizumab to Patients With Advanced Platinum-sensitive Ovarian Cancer

Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene

A Study to Examine Past Estimated Glomerular Filtration Rate (eGFR) Slope as a Risk Marker for Rapid Kidney Function Decline in People With Chronic Kidney Disease

Study of Cingal® and Triamcinolone Hexacetonide for the Relief of Knee Osteoarthritis Pain

A Study to Assess the Efficacy, Safety and Tolerability of Rozanolixizumab in Subjects With Chronic Inflammatory Demyelinating Polyradiculoneuropathy

Cannabidiol Oral Solution for the Treatment of Patients With Prader-Willi Syndrome

Family Health History in Diverse Care Settings (FHH)

Prospective Group-Matched Study With Belzupacap Sarotalocan (Bel-sar; AU-011) or Plaque Radiotherapy for Primary Indeterminate Lesions or Choroidal Melanoma (IL/ CM)

A Study of Bevacizumab in Combination With Chemotherapy for Treatment of Osteosarcoma