Clinical Trials in Colorado

Showing 3101-3120 of 8,657 trials

AETOS Shoulder System

NCT06319911

The goal of this study is to confirm the safety and performance of the AETOS Shoulder System for USA adoption. This is a prospective, open, adaptive, non-comparative, multi-centre investigation enrolling a maximum of 220 subjects in 2 cohorts (anatomic and reverse) at up to 15 sites. No intra-study comparator group will be included, and there will be no randomization

Shoulder OsteoarthritisShoulder Arthritis

Smith & Nephew, Inc.220 participantsStarted Mar 2024

San Francisco, California, United States • Denver, Colorado, United States • Columbus, Georgia, United States +2 more locations

COMPLETEDPhase 150 miles

MSB0011359C (M7824) in Metastatic or Locally Advanced Solid Tumors

NCT02517398

The main purpose of this Phase I study was to test MSB0011359C (M7824) at different dose levels to see if it is safe and well tolerated when given once every 2 weeks. Phase I means the study drug has not previously been given to humans or has only been given to a limited number of people, although it has been extensively studied in animals. Based on this information, it is hoped to find out which dose could be best for the treatment of patients. There are two parts of this research study: a dose-escalation part and an expansion part. Dose escalation means that the first people taking part in the study will receive low doses of the study drug, and as more people take part, the additional participants will receive a higher dose. This is done to find the safest dose for the study drug. Expansion means that after the dose-escalation part of the study has looked at the safety and effectiveness of different doses, many more people will be invited to take part in the study and will receive the study drug at the safest dose. Additional purposes of the study are to find out whether the study drug has anti-cancer effects and how the study drug is processed by the body.

Solid Tumors

EMD Serono Research & Development Institute, Inc.600 participantsStarted Aug 2015

Tucson, Arizona, United States • Escondido, California, United States • Sacramento, California, United States +115 more locations

AETOS Shoulder System

MSB0011359C (M7824) in Metastatic or Locally Advanced Solid Tumors

Find Trials by Condition in Colorado

Lithium for Suicidal Behavior in Mood Disorders

TelePrEP for At-risk Youth in Colorado

Defining the Molecular and Radiologic Phenotype of Progressive RA Interstitial Lung Disease

Study of an Anti-OX40 Monoclonal Antibody (KHK4083) in Subjects With Moderate to Severe Atopic Dermatitis

A Study of the Safety and Efficacy of GDC-0853 in Participants With Moderate to Severe Active Systemic Lupus Erythematosus

KHK2455 Alone and in Combination With Mogamulizumab in Subjects With Locally Advanced or Metastatic Solid Tumors

A Study Evaluating Tocilizumab in Pediatric Patients Hospitalized With COVID-19

Study of Subcutaneous Risankizumab Injection Compared to Oral Apremilast Tablets to Assess Change in Disease Activity And Adverse Events in Adult Participants With Moderate Plaque Psoriasis Who Are Candidates for Systemic Therapy

A Study Assessing the Efficacy and Safety of CBP-307 in Subjects With Moderate to Severe Ulcerative Colitis (UC)

Dendritic Cell/Myeloma Fusion Vaccine for Multiple Myeloma (BMT CTN 1401)

Hypofractionated Radiation Therapy in Preventing Recurrence in Patients With Breast Cancer After Surgery

RESILIENCE Trial: Evaluation of the Durability of Aortic Bioprostheses/Valves With RESILIA Tissue in Subjects Under 65

An Efficacy and Safety Study of 24 Week Treatment With Mavodelpar (REN001) in Primary Mitochondrial Myopathy Patients

A Study Evaluating JUVÉDERM® VOLUMA® XC Injectable Gel for Correction of Temple Hollowing in Adult Participants ≥ 22 Years Old

Testing the Addition of Immunotherapy With Hu5F9-G4 (Magrolimab) to the Usual PARP Inhibitor, Olaparib for Treatment of Metastatic or Recurrent Breast or Castrate-Resistant Prostate Cancer With BRCA Mutations

Treating Phantom Limb Pain Using Continuous Peripheral Nerve Blocks: A Department of Defense Funded Multicenter Study

Safety, Tolerability, and Efficacy Study in Subjects With Advanced or Metastatic Breast Cancer

CR845-310302: A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus