Clinical Trials in Chicago

Showing 18861-18880 of 20,493 trials

CMA-676 in Treating Older Patients With Acute Myeloid Leukemia in First Relapse

NCT00003673

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of CMA-676 in treating older patients who have acute myeloid leukemia that has recurred for the first time following at least 3 months of complete remission.

Leukemia

Pfizer55 participantsStarted Mar 1998

Tucson, Arizona, United States • Los Angeles, California, United States • Chicago, Illinois, United States +7 more locations

COMPLETEDPhase 32.2 miles

Study of Ivacaftor in Cystic Fibrosis Subjects Aged 6 to 11 Years With the G551D Mutation

NCT00909727

The purpose of this study was to evaluate the efficacy and safety of ivacaftor in subjects with cystic fibrosis aged 6 to 11 years who have the G551D mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Ivacaftor is a potent and selective potentiator of wild-type, G551D, F508del, and R117H forms of human CFTR protein. Potentiators are pharmacological agents that increase the chloride ion transport properties of the channel in the presence of cyclic adenosine monophosphate (AMP)-dependent protein kinase A (PKA) activation.

Cystic Fibrosis

Vertex Pharmaceuticals Incorporated52 participantsStarted Aug 2009

Birmingham, Alabama, United States • Atlanta, Georgia, United States • Chicago, Illinois, United States +26 more locations

CMA-676 in Treating Older Patients With Acute Myeloid Leukemia in First Relapse

Study of Ivacaftor in Cystic Fibrosis Subjects Aged 6 to 11 Years With the G551D Mutation

Find Trials by Condition in Chicago

Expanded Access Study of Satraplatin Plus Prednisone in Patients With Hormone Refractory Prostate Cancer (HRPC)

The Effect of Nasal Carbon Dioxide (CO2) in the Treatment of Mild Headache in People Who Experience Migraines

The Community United to Challenge Asthma

Skin Structure Infections With Suspected or Proven Methicillin-Resistant Staphylococcus Aureus (MRSA)

S0508: Thalidomide and Temozolomide in Treating Patients With Stage IV Melanoma That Cannot Be Removed By Surgery

S9804: Vinorelbine in Treating Patients With Stage IV Melanoma

Efficacy and Safety of Everolimus in Recipients of Heart Transplants to Prevent Acute and Chronic Rejection

Efficacy and Safety of Peginesatide Injection for the Maintenance Treatment of Anemia in Peritoneal Dialysis Participants Previously Treated With Epoetin.

Erlotinib vs. Standard Chemotherapy in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) and Eastern Cooperative Oncology Group (ECOG)Performance Status (PS) 2

Reducing Decompensation Events Utilizing Intracardiac Pressures in Patients With Chronic Heart Failure (HF) (REDUCEhf)

Study to Evaluate the Safety and Efficacy of DR-3001 Versus Placebo in Women With Overactive Bladder

Safety and Efficacy of an H1N1 Influenza Vaccine in People With Asthma

Gemcitabine With or Without CI-994 in Treating Patients With Advanced Pancreatic Cancer

Recombinant Human Antithrombin (rhAT) in Patients With Hereditary Antithrombin Deficiency Undergoing Surgery or Delivery

A Multicenter, Open-label Study to Determine the Effects of Lacosamide on Sleep in Healthy Subjects

Clinical Evaluation of NeoPlex4 Assay and NeoPlex System

Lantus Versus NPH: Comparison in Insulin Naive People Not Adequately Controlled With at Least One Oral Anti Diabetics (OAD) Treatment

Relative Bioavailability of Folic Acid and L-5-Methlytetrahydrofolate