Clinical Trials in Chicago

Showing 8321-8340 of 15,574 trials

Biobanking of Rett Syndrome and Related Disorders

NCT02705677

The overarching purpose of this study is to advance understanding of the natural history of Rett syndrome (RTT), MECP2-duplication disorder (MECP2 Dup), RTT-related disorders including CDKL5, FOXG1, and individuals with MECP2 mutations who do not have RTT. Although all these disorders are the result of specific genetic changes, there remains broad clinical variation that is not entirely accounted for by known biological factors. Additionally, clinical investigators currently do not have any biomarkers of disease status, clinical severity, or responsiveness to therapeutic intervention. To address these issues, biological materials (DNA, RNA, plasma, cell lines) will be collected from affected individuals and in some cases from unaffected family members, initial evaluation performed to identify additional biological factors contributing to disease severity, and these materials will be stored for future characterization.

Rett SyndromeMECP2 DuplicationCDKL5+1 more

University of Alabama at Birmingham752 participantsStarted Sep 2017

Birmingham, Alabama, United States • Oakland, California, United States • San Diego, California, United States +9 more locations

COMPLETEDNA2.2 miles

Red Raspberries on Insulin Action and Oxidative Stress

NCT02479035

The purpose of this study is to investigate the relative bioavailability and absorption/kinetic profile of red raspberry polyphenols consumed with a meal and further to determine the relationship of these findings on meal-associated metabolic- oxidative- and inflammatory- responses in relatively insulin sensitive and insulin resistant individuals.

Insulin Resistant

Clinical Nutrition Research Center, Illinois Institute of Technology40 participantsStarted Jun 2015

Chicago, Illinois, United States

Biobanking of Rett Syndrome and Related Disorders

Red Raspberries on Insulin Action and Oxidative Stress

Find Trials by Condition in Chicago

Natural History of Rett Syndrome & Related Disorders

Berberine Chloride in Preventing Colorectal Cancer in Patients With Ulcerative Colitis in Remission

Open Label, Phase III Study of NABI-IGIV 10% [Immune Globulin Intravenous(Human), 10%] In Subjects With Primary Immune Deficiency Disorders (PIDD)

Systemic Chemotherapy and Subtenon Carboplatin, and Local Ophthalmic Therapy in Children With Intraocular Retinoblastoma

This is a Safety and Tolerability Study Evaluating a New Treatment for Subjects With Mild to Moderate Alzheimer's Disease

Role of Rehabilitation in Concussion Management: A Randomized Controlled Trial

A Study To Investigate Tanezumab In Patients With Interstitial Cystitis/ Painful Bladder Syndrome

Docetaxel and Carboplatin for Patients With mCRPC and DNA-Repair Deficiencies

Varlitinib in Combination With Capecitabine for Advanced or Metastatic Biliary Tract Cancer

Safety and Efficacy of Sirolimus for HIV Reservoir Reduction in Individuals on Suppressive Antiretroviral Therapy (ART)

Telmisartan to Reduce AIDS-Related Fibrotic and Inflammatory Contributors (TRAFIC Study)

A Study of LY3295668 Erbumine in Participants With Extensive-stage Small-Cell Lung Cancer

Study to Test the Safety, Tolerability and Efficacy of UCB7665 in Subjects With Moderate to Severe Myasthenia Gravis

Bioequivalence Study of PF-06651600 Capsules Relative to Tablets and Estimation of Food Effect on Capsules.

A Study Investigating the Efficacy and Safety of Upadacitinib (ABT-494) Given With Methotrexate (MTX) in Adults With Rheumatoid Arthritis Who Have Had an Inadequate Response to MTX Alone

Tesetaxel Plus Reduced Dose of Capecitabine in Patients With HER2 Negative, HR Positive, LA/MBC

Maraviroc to Augment Rehabilitation Outcomes After Stroke

Preventing Excessive Gestational Weight Gain in Obese Women