Clinical Trials in Chicago

Showing 7841-7860 of 20,493 trials

Healthy Combine Study

NCT03136705

STUDY SUMMARY Title: EFFECTS OF NICOTINAMIDE AND LANTHANUM CARBONATE ON PHOSPHORUS HOMEOSTASIS Protocol Number:STU00090161 Phase: Phase 1, detailed physiologic study Methodology: double blind, randomized, placebo-controlled, 2x2 factorial Study Duration: 12-18 months (to complete the entire study protocol) Study Center: Single-center Objectives: Define short-term effects of the interventions (lanthanum carbonate and nicotinamide) on indices of phosphate handling Number of Subjects: 80 Diagnosis and Main Inclusion Criteria: Healthy volunteers Study Product(s), Dose,Route, Regimen: Nicotinamide, 750 mg by mouth twice daily, Lanthanum carbonate, Fosrenol, 1000 mg by mouth three times daily with meals Duration of administration: 2 weeks (length of time study participants are enrolled in study) Reference therapy: reference is a placebo Statistical Methodology: Repeated measures analysis using mixed linear models

Healthy

Northwestern University39 participantsStarted Feb 2016

Chicago, Illinois, United States

TERMINATEDPhase 1/22.2 miles

Pilot Immunotherapy Study With Letetresgene Autoleucel (Lete-cel, GSK3377794)T-cells in New York Esophageal Squamous Cell Carcinoma-1 (NY-ESO-1)/ LAGE-1a-positive Advanced Non-small Cell Lung Cancer (NSCLC) Either Alone or in Combination With Pembrolizumab

NCT03709706

This trial will evaluate safety and tolerability of letetresgene autoleucel (GSK3377794) with or without pembrolizumab in participants with non-small cell lung cancer.

Neoplasms

GlaxoSmithKline34 participantsStarted Dec 2018

Duarte, California, United States • La Jolla, California, United States • Sacramento, California, United States +28 more locations

Healthy Combine Study

Pilot Immunotherapy Study With Letetresgene Autoleucel (Lete-cel, GSK3377794)T-cells in New York Esophageal Squamous Cell Carcinoma-1 (NY-ESO-1)/ LAGE-1a-positive Advanced Non-small Cell Lung Cancer (NSCLC) Either Alone or in Combination With Pembrolizumab

Find Trials by Condition in Chicago

Afimoxifene in Reducing the Risk of Breast Cancer in Women With Mammographically Dense Breast

Reducing Opioid Mortality in Illinois

Vorinostat, Temozolomide, or Bevacizumab in Combination With Radiation Therapy Followed by Bevacizumab and Temozolomide in Young Patients With Newly Diagnosed High-Grade Glioma

Guadecitabine and Pembrolizumab in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Journey™ UNI Post Market Clinical Follow-Up

Prevalence of PD-L1 Expression in Patients With Advanced Urothelial Carcinoma

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin as Adjunct Therapy to a Topical Corticosteroid for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis

Safety and Efficacy Comparison of Docetaxel and Ixabepilone in Non Metastatic Poor Prognosis Breast Cancer

Development and Testing of a Pediatric Cervical Spine Injury Risk Assessment Tool

Dose-finding Study of SPK-8016 Gene Therapy in Patients With Hemophilia A to Support Evaluation in Individuals With FVIII Inhibitors

ELUCIDATE FFRct Study

Diabetes Study of Linagliptin and Empagliflozin in Children and Adolescents (DINAMO)TM

Pilot Prospective Study: Long-term Health of Living Kidney Donors

Observational Registry to Assess the Durability of Effect of CXL in Patients With Corneal Ectasia After Refractive Surgery

Evaluating Two Multifocal Daily Disposable Contact Lenses

A Comparative Study Between PF-06410293 and Humira® in Combination With Methotrexate in Participants With Active Rheumatoid Arthritis

Gene Therapy With hLB-001 in Pediatric Patients With Severe Methylmalonic Acidemia

Nivolumab Ipilimumab in Patients With hyperMutated Cancers Detected in Blood (NIMBLe)