Clinical Trials in Chicago

Showing 7541-7560 of 15,574 trials

Shared Decision Aid for Post-Total Knee Arthroplasty Opioid Prescribing

NCT04564729

This will be a randomized controlled clinical trial in patients who have undergone primary unilateral total knee arthroplasty at Brigham and Women's Faulkner Hospital, Brigham and Women's Hospital and University of Chicago Medical Center. Study subjects will receive either a shared decision aid (SDA) about pain management or standard of care at the time of discharge. The impact of the SDA on the number of leftover opioid pills on postoperative day 30 and average NRS pain score on postoperative day 7 will be assessed.

Knee Arthroplasty, TotalAnalgesiaOpioid Use, Unspecified

Brigham and Women's Hospital142 participantsStarted Nov 2020

Chicago, Illinois, United States • Boston, Massachusetts, United States

COMPLETEDPhase 32.2 miles

Radiation Therapy With or Without Optional Tamoxifen in Treating Women With Ductal Carcinoma in Situ

NCT00003857

RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Estrogen can stimulate the growth of breast cancer cells. Hormone therapy using tamoxifen may fight breast cancer by blocking the uptake of estrogen by the tumor cells. It is not yet known if radiation therapy is more effective than observation, with or without tamoxifen, in treating ductal carcinoma in situ. PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy with that of observation, with or without tamoxifen, in treating women who have ductal carcinoma in situ.

Breast Cancer

Radiation Therapy Oncology Group636 participantsStarted Dec 1999

Mobile, Alabama, United States • Fairbanks, Alaska, United States • Phoenix, Arizona, United States +366 more locations

Shared Decision Aid for Post-Total Knee Arthroplasty Opioid Prescribing

Radiation Therapy With or Without Optional Tamoxifen in Treating Women With Ductal Carcinoma in Situ

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Combination Chemotherapy With or Without Hypofractionated Radiation Therapy Before Surgery in Treating Patients With Pancreatic Cancer

Long-Term Treatment and Follow up of Subjects Completing 24 Months of Treatment With Tesevatinib on Study KD019-101

Efficacy and Safety of Vedolizumab Subcutaneously (SC) as Maintenance Therapy in Ulcerative Colitis

Improving Women's and Children's Health Via Biobanking and Electronic Registry

Study Of PF-06817024 In Healthy Subjects, In Patients With Chronic Rhinosinusitis With Nasal Polyps And in Patients With Atopic Dermatitis

A Study to Evaluate Efficacy and Safety of AG-348 in Not Regularly Transfused Adult Participants With Pyruvate Kinase Deficiency (PKD)

Study to Evaluate Dupilumab Monotherapy in Pediatric Patients With Peanut Allergy

Combination Entecavir and Peginterferon Therapy in HBeAg-Positive Immune-Tolerant Adults With Chronic Hepatitis B

Safety and Efficacy of ATIR101 as Adjunctive Treatment to Blood Stem Cell Transplantation From a Haploidentical Family Donor Compared to Post-transplant Cyclophosphamide in Patients With Blood Cancer

An Investigational Immunotherapy Study of BMS-986299 Alone and in Combination With Nivolumab and Ipilimumab in Participants With Solid Cancers That Have Spread or Cannot be Removed

Vitamin D Supplementation for Adults With Neurofibromatosis Type 1 (NF1)

Adherence With Continuous-dose Oral Contraceptive: Evaluation of Self-Selection and Use

The TOGETHER Project - Liver

Objective Pain Measurement Using a Wearable Biosensor and a Mobile Platform in Patients With Endometriosis

Evaluation of EpiBone-CMF for Mandibular Ramus Reconstruction

Kidney Precision Medicine Project

RSV F Vaccine Maternal Immunization Study in Healthy Third-trimester Pregnant Women.

First in Human Testing of Dose-escalation of SAR440234 in Patients With Acute Myeloid Leukemia, Acute Lymphoid Leukemia and Myelodysplastic Syndrome