Clinical Trials in Chicago

Showing 5421-5440 of 20,493 trials

Effects of High-intensity Gait Training on Fatigue, Gait, and Neuroplasticity in People With Multiple Sclerosis

NCT06264336

Nearly 1 million individuals in the United States have multiple sclerosis, which causes fatigue and problems with walking. Fatigue and walking problems are poorly treated, but exercise training, particularly high-intensity walking exercise, may help. This provide insight into whether high-intensity walking exercise can improve fatigue and walking problems in people with multiple sclerosis, which could improve quality of life and reduce economic burden.

Multiple Sclerosis

University of Illinois at Chicago20 participantsStarted Mar 2024

Chicago, Illinois, United States

RECRUITINGPhase 12.2 miles

Personalized Autologous Transplant for Multiple Myeloma

NCT04483206

This phase I trial studies the best dose and side effects of mephalan in treating patients with multiple myeloma who are undergoing stem cell transplant. Chemotherapy drugs, such as mephalan, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. This trial uses a new method of dosing that is based on analysis of each individual's blood levels of melphalan after receiving a part of the dose, termed pharmacokinetic analysis. This may help to learn more about how to dose melphalan correctly and which patients are likely to benefit from a personalized dose.

Multiple Myeloma

Emory University90 participantsStarted May 2021

Atlanta, Georgia, United States • Chicago, Illinois, United States

RECRUITINGPhase 2/32.2 miles

Double-blind, Randomized Trial of PRAX-628 in Adults With Focal Seizures to Evaluate Efficacy and Safety (POWER1)

NCT06999902

A Double-Blind, Randomized, Multicenter, Trial Evaluating the Efficacy and Safety of PRAX-628 in Adults With Focal Seizures (POWER1)

Focal Seizure

Praxis Precision Medicines230 participantsStarted Dec 2024

Phoenix, Arizona, United States • DeLand, Florida, United States • Miami Lakes, Florida, United States +23 more locations

Effects of High-intensity Gait Training on Fatigue, Gait, and Neuroplasticity in People With Multiple Sclerosis

Personalized Autologous Transplant for Multiple Myeloma

Double-blind, Randomized Trial of PRAX-628 in Adults With Focal Seizures to Evaluate Efficacy and Safety (POWER1)

Find Trials by Condition in Chicago

Study of a Respiratory Syncytial Virus Candidate Encapsulated in a Lipid Nanoparticle Based Formulation in Adults Aged 18 to 50 Years and 60 Years and Older

IVUS-Guided Treatment for Percutaneous Vascular Interventions

Prospective Multi-Center Study of Short-Term Outcomes After Complex Cholecystectomy

Study of the Relay Pro® Thoracic Stent-Graft in Subjects With Traumatic Injury of the Descending Thoracic Aorta

Prospective Observational Cohort Study of Fetal Atrial Flutter & Supraventricular Tachycardia

ECMO Hemostatic Transfusions in Children

Global Utilization And Registry Database for Improved heArt preservatioN

Long Term Extension Trial of Setmelanotide

A Study to Evaluate Efficacy and Safety of Deucravacitinib in Participants With Alopecia Areata

A Study on the Safety, Effectiveness and Immune Response of Meningococcal Combined ABCWY Vaccine in Healthy Adolescents and Adults

Spatz3 Adjustable Balloon System® (Spatz3) Post Approval Study

MAGIC Ruxolitinib for aGVHD

Early Feasibility Study of the RelayBranch Thoracic Stent-Graft System

Combined Modality Therapy for Patients With With HIV and Stage I, Stage II, or Stage III Anal Cancer

Assessment of ANK-700 in Patients With Relapsing Remitting Multiple Sclerosis

Internet-Based Lifestyle Intervention to Eradicate Obese Frailty in Prostate Cancer Survivors, iLIVE

Validation of ClarityDX Prostate as a Reflex Test to Refine the Prediction of Clinically-significant Prostate Cancer