Clinical Trials in Chicago

Showing 521-540 of 20,493 trials

Clinical Study of Edwards Cardioband FIT Valve Repair System

NCT03382457

Clinical Study of the Edwards Cardioband FIT Repair System

Edwards Lifesciences75 participantsStarted Jul 2018

Chicago, Illinois, United States • Rochester, Minnesota, United States • Morristown, New Jersey, United States +6 more locations

Active Not RecruitingPhase 2/32.2 miles

INBRX-106 in Combination With Pembrolizumab in First-line PD-L1 CPS≥20 HNSCC

NCT06295731

This seamless phase 2/3 randomized controlled study will evaluate the efficacy and safety of the hexavalent OX40 agonist antibody INBRX-106 combined with the anti-PD-1 antibody pembrolizumab versus pembrolizumab (+ placebo in phase 3) as first-line treatment for patients with locally advanced recurrent or metastatic head and neck squamous cell carcinoma (R/M HSNSCC) incurable by local therapies, expressing PD-L1 with a combined proportion score (CPS) ≥20.

Head and Neck Squamous Cell Carcinoma (HNSCC)

Inhibrx Biosciences, Inc410 participantsStarted May 2024

Duarte, California, United States • Los Angeles, California, United States • Sacramento, California, United States +84 more locations

Clinical Study of Edwards Cardioband FIT Valve Repair System

INBRX-106 in Combination With Pembrolizumab in First-line PD-L1 CPS≥20 HNSCC

Find Trials by Condition in Chicago

HF Patients With LVADs Being Treated With SGLT2i

Testing the Addition of Immunotherapy Before Surgery for Patients With Sarcomatoid Mesothelioma

A Study to Evaluate TAR-210 Versus Intravesical Chemotherapy Treatment in Participants With High Risk Non-Muscle-Invasive Bladder Cancer

A Study to Test if Trevogrumab or Trevogrumab With Garetosmab When Taken With Semaglutide is Safe and How Well They Work in Adult Patients With Obesity for Weight Loss, Fat Loss, and Lean Mass Preservation

A Phase 1/2 Study of GEN1286 in Patients With Advanced Solid Tumors

A Study of Selexipag as Add-On Treatment to Standard of Care in Children With Pulmonary Arterial Hypertension

A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Chronic Migraine

Clesrovimab (MK-1654) in Infants and Children at Increased Risk for Severe Respiratory Syncytial Virus (RSV) Disease (MK-1654-007)

Evaluating Combination of Nivolumab and Axatilimab in Patients With Relapsed/Refractory Classical Hodgkin Lymphoma

An Extension Study of Donidalorsen (IONIS-PKK-LRx) in Participants With Hereditary Angioedema

A Study of Navenibart (STAR-0215) in Participants With Hereditary Angioedema

A Study of REC-1245 in Participants With Unresectable, Locally Advanced, or Metastatic Cancer

A Study of JNJ-80948543, a T-cell Redirecting CD79b x CD20 x CD3 Trispecific Antibody, in Participants With Non-Hodgkin Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL)

Study to Evaluate Safety, Tolerability, and Optimal Dose of Candidate GBM Vaccine VBI-1901 in Recurrent GBM Subjects

STrategies for Catheter Ablation of peRsistent Atrial Fibrlllation

A Safety Study of PF-08046044/SGN-35C in Adults With Advanced Cancers

Comparison of Outcomes of Management of Bowel Obstruction

A Study to Learn About the Study Medicine Called PF-08046032 in People With Advanced Cancers