Clinical Trials in Chicago

Showing 4141-4160 of 20,493 trials

Veri-T: A Trial of Verdiperstat in Patients With svPPA Due to TDP-43 Pathology

NCT05184569

The purpose of the study is to test the safety and tolerability of twice daily Verdiperstat in patients with semantic variant primary progressive aphasia (svPPA) due to frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP). Three-fourths of the participants will receive Verdiperstat and one-fourth will receive Placebo during the 24-week treatment duration.

Semantic Dementia

Peter Ljubenkov, MD64 participantsStarted Apr 2022

San Francisco, California, United States • Chicago, Illinois, United States • Rochester, Minnesota, United States +2 more locations

RECRUITINGPhase 12.2 miles

Study of JANX008 in Subjects With Advanced or Metastatic Solid Tumor Malignancies

NCT05783622

This study is a first-in-human (FIH), Phase 1/1b, open-label, multicenter dose escalation and dose expansion study to assess the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary anti-tumor activity of JANX008 in adult subjects with advanced or metastatic carcinoma expressing EGFR.

Non-Small Cell Lung CancerRenal Cell CarcinomaSquamous Cell Carcinoma of the Head and Neck+4 more

Janux Therapeutics130 participantsStarted Apr 2023

Duarte, California, United States • Sacramento, California, United States • San Diego, California, United States +15 more locations

Veri-T: A Trial of Verdiperstat in Patients With svPPA Due to TDP-43 Pathology

Study of JANX008 in Subjects With Advanced or Metastatic Solid Tumor Malignancies

Find Trials by Condition in Chicago

A Study to Confirm Safety and Efficacy of Lecanemab in Participants With Early Alzheimer's Disease

Effectiveness and Safety Study of Tezepelumab in Adults & Adolescent Participants With Severe Asthma in the United States

Traditional Versus Early Aggressive Therapy for Multiple Sclerosis Trial

ALTUS: Performance of a Multi- Target Hepatocellular Carcinoma (HCC) Test in Subjects With Increased Risk

Long Term, Extension Study of the Safety and Efficacy of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type

A Study of LY3841136 in Overweight and Obese Participants

Safety and Tolerability of RPE Stem Cell-derived RPE(RPESC-RPE) Transplantation in Patients With Dry Age-related Macular Degeneration (AMD)

Senolytics To slOw Progression of Sepsis (STOP-Sepsis) Trial

A Study of Inhaled AZD8630 in Adolescents With Asthma

A Study of CLE-100 (Oral Esketamine) in Addition to Standard Antidepressant Drug for Major Depressive Disorder - CLEO Study

Nafamostat Efficacy in Phase 3 Registrational CRRT Study

Safety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) in Subjects With Dim Light Vision Disturbances

Interferon-γ (IFN-γ) With Donor Leukocyte Infusion to Treat Relapsed Acute Myeloid Leukemia and Myelodysplastic Syndromes Post Allogeneic Hematopoietic Stem Cell Transplantation

Intent of Surgery for IPMN

A Study of Andecaliximab in Participants With Fibrodysplasia Ossificans Progressiva (FOP)

A Randomized Phase II Study Of Bruton Tyrosine Kinase Inhibitor With Or Without Venetoclax In Veterans With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

Placebo-Controlled Trial of IFx-Hu2.0 Followed By Pembrolizumab In Checkpoint Inhibitor Naïve Participants With Advanced Or Metastatic Merkel Cell Carcinoma

A Study to Learn About the Occurrence of ADHD in Adults With Mental Conditions and Their Quality of Life