Clinical Trials in Chicago

Showing 3981-4000 of 9,860 trials

Pediatric REPlAcement of the PulmonaRy ValvE in Tetralogy of Fallot -

NCT03634072

Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart defect with the vast majority of survivors of corrective surgery left with some degree of right ventricular (RV) volume overload due to pulmonary regurgitation (PR) which cause RV enlargement with right heart failure, diminished biventricular function, ventricular arrhythmia, sudden death and decreased exercise performance over time. Pulmonary valve replacement (PVR) has been thought to ameliorate these complications but the timing of replacement has yet to be determined with equipoise at the moment in this decision making process. As nearly all studies in this regard are retrospective with much less data in pediatric TOF than adults, this pilot trial sets the stage to create a prospective randomized trial in the teenage years.

Tetralogy of Fallot

Children's Hospital of Philadelphia1 participantsStarted Jul 2018

Washington D.C., District of Columbia, United States • Atlanta, Georgia, United States • Chicago, Illinois, United States +3 more locations

UNKNOWNNA2.2 miles

Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts: The ECLIPSE Trial

NCT03108456

This trial will evaluate Orbital Atherectomy compared to conventional balloon angioplasty technique for the treatment of severely calcified lesions prior to implantation of drug-eluting stents (DES).

Coronary Artery DiseaseIschemic Heart DiseaseNon ST Segment Elevation Myocardial Infarction

Abbott Medical Devices2,005 participantsStarted Mar 2017

Birmingham, Alabama, United States • Chandler, Arizona, United States • Phoenix, Arizona, United States +101 more locations

Pediatric REPlAcement of the PulmonaRy ValvE in Tetralogy of Fallot -

Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts: The ECLIPSE Trial

Find Trials by Condition in Chicago

Base-in Prism Spectacles for Intermittent Exotropia

Pivotal Trial of a Digital Therapeutic for the Treatment of Type 2 Diabetes

The CASCADE HF Soft Launch and Calibration Phase I and II

Study of the Effect of SZC on Serum Potassium and Serum Bicarbonate in Patients With Hyperkalemia and Metabolic Acidosis Associated With Chronic Kidney Disease

Timing of Inguinal Hernia Repair in Premature Infants

Bendamustine in Combination With Bortezomib and Pegylated Liposomal Doxorubicin for Multiple Myeloma

MEDI9447(Oleclumab) Pancreatic Chemotherapy Combination Study.

VasQ External Support for Arteriovenous Fistula

Transnasal Cooling for Migraine

A Study of SLS-002 (Intranasal Racemic Ketamine) in Adults With Major Depressive Disorder at Imminent Risk of Suicide

A Study of AND017 to Treat Anemia in Non-dialysis-Dependent Chronic Kidney Disease (NDD-CKD) Patients

Study to Evaluate R2R01 Plus Terlipressin Versus Terlipressin Alone in Patients With Hepatorenal Syndrome

An Study to Evaluate the Safety and Efficacy of Copanlisib in Combination With Nivolumab in Patients With Advanced Solid Tumors

Phase 1 Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Multiple Oral Doses of MGL-3196 in Subjects With Varying Degrees of Hepatic Impairment and Healthy Matched Control Subjects

Paclitaxel, Cyclophosphamide & Doxorubicin, Autologous Dendritic Cells & Surgery in Stage II/III Breast Cancer (Women)

Addressing Intimate Partner Violence Among Women Veterans

Comparison Across Multiple Types of Sleep Deprivation

Telomere Associated Variables (TAVs) in Prostate Cancer