Clinical Trials in Chicago

Showing 2601-2620 of 9,860 trials

Watermelon Dose Response Blood Pressure Study

NCT05892328

1. Primary outcome: To evaluate the dose response effects of watermelon flesh in regulating Blood Pressure (BP) in individuals with pre-hypertension. 2. Secondary outcomes: To study the dose-response effects of watermelon flesh intake on cardio-metabolic risk factors including plasma metabolic markers, lipid profile and nitrate/nitrite levels in individuals with pre-hypertension.

Pre-hypertensionCardiovascular Diseases

Clinical Nutrition Research Center, Illinois Institute of Technology36 participantsStarted Apr 2023

Chicago, Illinois, United States

RECRUITINGPhase 22.2 miles

Study to Evaluate the Efficacy, Safety, and Tolerability of Efzofitimod in Patients With Systemic Sclerosis (SSc)-Related Interstitial Lung Disease (ILD) (SSc-ILD)

NCT05892614

This is a 2-Part study with Part A, a double-blind, randomized, placebo-controlled, PoC study to evaluate the efficacy, safety, and tolerability of efzofitimod in patients with SSc-ILD. The primary objective of the study is to evaluate the PoC for efficacy in a population with SSc-ILD. While improvement of ILD is the outcome of interest, the study will also evaluate changes in the skin. After initial screening (up to 4 weeks), approximately 25 eligible participants will be randomized 2:2:1 to 1 of 2 active (experimental) dose arms or placebo, administered every 4 weeks up to and including Week 20. Part B is an optional open-label extension to Part A in which participants can receive 450 mg efzofitimod every 4 weeks for 6 doses.

Interstitial Lung Disease

aTyr Pharma, Inc.25 participantsStarted Oct 2023

Los Angeles, California, United States • San Diego, California, United States • Miami, Florida, United States +12 more locations

Watermelon Dose Response Blood Pressure Study

Study to Evaluate the Efficacy, Safety, and Tolerability of Efzofitimod in Patients With Systemic Sclerosis (SSc)-Related Interstitial Lung Disease (ILD) (SSc-ILD)

Find Trials by Condition in Chicago

Circulating Tumor DNA Testing in Predicting Treatment for Patients With Stage IIA Colon Cancer After Surgery

Clinical Impact of Respiratory-Swallow Training on Refractory Dysphagia in Oropharyngeal Head and Neck Cancer

A Study of PF-07260437 in Advanced or Metastatic Solid Tumors

Precision-T: A Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies

Phase II Study to Evaluate Efficacy and Safety of D-0120 in Combination With Allopurinol in Subjects With Gout

Individually-guided Hearing Aid Fitting

Safety and Efficacy Study of reSept ASD Occluder for Treating Secundum ASD

Venting Effects on Speech Performance

Ferric Citrate and Chronic Kidney Disease in Children

HOPE-B: Trial of AMT-061 in Severe or Moderately Severe Hemophilia B Patients

AltaValve Pivotal Trial

Immunotherapy Before Transplantation for Skin Cancer Prevention in Organ Transplant Recipients

A Phase 1/2 Study to Evaluate ALN-KHK in Overweight to Obese Healthy Volunteers and Obese Patients With T2DM

COVID-19 VaccinE Response in Rheumatology Patients

Retrospective Clinical Trial Comparing Radiologists' Diagnosis Accuracy in Lung Cancer Screening Population With and Without the Help of an AI/ML Tech-based SaMD

Repurposing Nucleoside Reverse Transcriptase Inhibitors for Treatment of AD

A Study of Copanlisib Combined With Rucaparib in Patients With Metastatic Castration-resistant Prostate Cancer

Tolerability and Feasibility Pilot Clinical Study of a Large-Diameter Nerve Cap for Protecting and Preserving Terminated Nerve Ends