Clinical Trials in Chicago

Showing 2161-2180 of 9,860 trials

CD40 Agonist, Flt3 Ligand, and Chemotherapy in HER2 Negative Breast Cancer

NCT05029999

This research study is being done to find out if the immunotherapy drugs called CDX-301 and CDX-1140 in combination with the standard chemotherapy treatment pegylated liposomal doxorubicin (PLD, Doxil) are safe and effective at controlling the cancer in patients with metastatic triple Human Epidermal Growth Factor Receptor 2 (HER2) negative breast cancer, and to determine a safe dose and treatment schedule of the three drugs. This research study will also test how your immune system responds to these treatments alone and in combination.

HER2-negative Breast CancerMetastatic Breast Cancer

University of Texas Southwestern Medical Center30 participantsStarted Apr 2022

Chicago, Illinois, United States • Baltimore, Maryland, United States • Chapel Hill, North Carolina, United States +4 more locations

COMPLETED2.2 miles

Nonalcoholic Fatty Liver Disease (NAFLD) Database 3

NCT04454463

The NAFLD Database 3 will enroll approximately 1500 adult patients and 750 pediatric patients suspected or known to have NAFLD or NASH-related cirrhosis. To elucidate, through the cooperative effort of a multidisciplinary and multicenter group of collaborators, the etiology, natural history, diagnosis, treatment, and prevention of NAFLD, and in particular its more severe form of NASH and its complications.

Liver Diseases

Johns Hopkins Bloomberg School of Public Health1,649 participantsStarted Nov 2020

La Jolla, California, United States • Los Angeles, California, United States • San Diego, California, United States +13 more locations

CD40 Agonist, Flt3 Ligand, and Chemotherapy in HER2 Negative Breast Cancer

Nonalcoholic Fatty Liver Disease (NAFLD) Database 3

Find Trials by Condition in Chicago

A Study of Seltorexant Compared to Quetiapine XR as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant Therapy

Supporting Transitions to Primary Care Among Under-resourced, Postpartum Women (STEP-UP)

Let's E.A.T.! (Eating With Assistive Technology): An Intervention to Support Children With Feeding Tubes and Tracheostomies

Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction Trial

A Study to Assess Adverse Events and Change in Disease Condition of Mesalamine Capsules in Children Aged 5 to 17 Years With Ulcerative Colitis

Observation Study in Patients Age 0-5 Years With LAMA2-related Congenital Muscular Dystrophy

Transcutaneous Electrical Stimulation for Stroke Patients

The MOOD Study - External Combined Occipital and Trigeminal Nerve Stimulation (eCOT-NS) for the Treatment of Major Depressive Disorder (MDD)

Evolution of the Chicago Classification: Bridging Physiology and Mechanics

A Study to Investigate Safety and Tolerability of NDX-3315 and NDX-3324 in Healthy Participants and Patients With Eosinophilic Esophagitis

Combining Ipilimumab With Abiraterone Acetate Plus Prednisone in Chemotherapy and Immunotherapy-naïve Patients With Progressive Metastatic Castration-resistant Prostate Cancer

A Study to Evaluate the Efficacy and Safety of 2 Doses of EYE103 Compared With Ranibizumab (0.5 mg) in Participants With DME

To Assess the Efficacy and Safety of INCB054707 in Participants With Hidradenitis Suppurativa

A Study to Evaluate the Safety and Tolerability of Maximal Use Ruxolitinib Cream

Ropeginterferon Alfa-2b (P1101) vs. Anagrelide in Essential Thrombocythemia Patients With Hydroxyurea Resistance or Intolerance

A Study to Evaluate the Safety and Efficacy of CT1812 in Subjects With Mild to Moderate Alzheimer's Disease.

A Phase 1/2 Study of INCB001158 in Combination With Chemotherapy in Subjects With Solid Tumors

Proton Beam Radiotherapy for Medulloblastoma and Pineoblastoma