Clinical Trials in California

Showing 1481-1500 of 5,448 trials

User Acceptability Evaluation of Pseudophakic Patients Previously Implanted With the TECNIS Odyssey IOL

NCT06005675

Prospective collection of data from medical records, multicenter, post-market clinical follow-up study.

Johnson & Johnson Surgical Vision, Inc.44 participantsStarted Sep 2023

Bakersfield, California, United States • Venice, Florida, United States • Mt. Pleasant, South Carolina, United States +1 more locations

COMPLETEDPhase 4158 miles

A Study of Esketamine Nasal Spray, Administered as Monotherapy, in Adult Participants With Treatment-resistant Depression

NCT04599855

The purpose of this study is to evaluate the efficacy of each individual dose of esketamine nasal spray, 56 milligram (mg) and 84 mg, compared with placebo nasal spray in improving depressive symptoms in participants with treatment resistant depression (TRD), as assessed by the change from baseline in the Montgomery-Asberg Depression Rating Scale (MADRS) total score from Day 1 (prerandomization) to the end of the 4 week double-blind treatment phase (Day 28).

Depressive Disorder, Treatment-Resistant

Janssen Research & Development, LLC477 participantsStarted Nov 2020

Birmingham, Alabama, United States • Huntsville, Alabama, United States • Little Rock, Arkansas, United States +51 more locations

User Acceptability Evaluation of Pseudophakic Patients Previously Implanted With the TECNIS Odyssey IOL

A Study of Esketamine Nasal Spray, Administered as Monotherapy, in Adult Participants With Treatment-resistant Depression

Find Trials by Condition in California

Long-Term Follow-up Study of ADVM-022 in DME (INFINITY-EXT)

Long-term Follow-up Study With Darvadstrocel in the Treatment of Complex Perianal Fistula

A Trial of Setanaxib in Patients With Primary Biliary Cholangitis (PBC) and Liver Stiffness

A Study of CTX-009 in Combination With Paclitaxel in Adult Patients With Unresectable Advanced, Metastatic or Recurrent Biliary Tract Cancers (COMPANION-002)

A Multiple-dose Study of ASP8374, an Immune Checkpoint Inhibitor, as a Single Agent and in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors

Efficacy Study of Nivolumab Compared to Ipilimumab in Prevention of Recurrence of Melanoma After Complete Resection of Stage IIIb/c or Stage IV Melanoma

Carvedilol in Preventing Heart Failure in Childhood Cancer Survivors

Clinical Trial Readiness to Solve Barriers to Drug Development in FSHD

Ph 2 Study of the Safety and Efficacy of Three HU6 Dose Levels and Placebo in Nonalcoholic Steatohepatitis

DALY II USA/ MB-CART2019.1 for DLBCL

A Study of JNJ-73763989 + Nucleos(t)Ide Analog in Participants Co-Infected With Hepatitis B and Hepatitis D Virus

HiLo: Pragmatic Trial of Higher vs Lower Serum Phosphate Targets in Patients Undergoing Hemodialysis

Safety and Efficacy of GS-100 Gene Therapy in Patients With NGLY1 Deficiency

Post-trial Access Program of Idursulfase-IT Along With Elaprase in Children With Hunter Syndrome

Gene Therapy in Treating Patients With Human Immunodeficiency Virus-Related Lymphoma Receiving Stem Cell Transplant

A Multi-center, Open-label Study of Oral ENMD-2076 for the Treatment of Patients With Advanced Fibrolamellar Carcinoma

Burn Validation Study

Immune-mediated Pathogenic Mechanisms of Neuro-PASC in Veterans