Clinical Trials in Baltimore

Showing 12121-12140 of 20,142 trials

Renal Effects of Intrarenal Nesiritide

NCT00270829

The impact of nesiritide in CHF is unclear, but it is possible that systemic vasodilation leads to adverse consequences even if the direct renal effects are positive. Therefore, this study will look at the effects of direct intrarenal administration of nesiritide on GFR and RPF.

Heart Failure, Congestive

University of Maryland, Baltimore2 participantsStarted Dec 2005

Baltimore, Maryland, United States

COMPLETEDPhase 3< 1 mile

Fulvestrant With or Without Lapatinib in Treating Postmenopausal Women With Stage III or Stage IV Breast Cancer That is Hormone Receptor-Positive

NCT00390455

This randomized phase III trial studies fulvestrant and lapatinib to see how well they work compared to fulvestrant and a placebo in treating postmenopausal women with stage III or stage IV breast cancer that is hormone receptor-positive. Estrogen can cause the growth of breast cancer cells. Hormone therapy using fulvestrant may fight breast cancer by lowering the amount of estrogen the body makes. Lapatinib may stop the growth of breast cancer cells by blocking some of the enzymes needed for cell growth. It is not yet known whether fulvestrant is more effective with or without lapatinib in treating breast cancer.

Estrogen Receptor PositiveHER2 Positive Breast CarcinomaHER2/Neu Negative+5 more

National Cancer Institute (NCI)295 participantsStarted Sep 2006

Little Rock, Arkansas, United States • Arroyo Grande, California, United States • Arroyo Grande, California, United States +365 more locations

Renal Effects of Intrarenal Nesiritide

Fulvestrant With or Without Lapatinib in Treating Postmenopausal Women With Stage III or Stage IV Breast Cancer That is Hormone Receptor-Positive

Find Trials by Condition in Baltimore

Pediatric Open-Label Extension Study

A Pediatric Longitudinal Evaluation to Assess the Long-Term Safety of Protopic for the Treatment of Atopic Dermatitis

Levels of Bisphenol A in Urine and Saliva Following Placement of Composite Restorations

Message Testing for Tobacco-Related Corrective Statements

Insulin Resistance and Atherosclerosis in Women With Lupus

Genetic Analysis of Patients With Pseudoxanthoma Elasticum

The Experience of Caregivers of Children With Down Syndrome

Safety of ON 01910.Na in Patients With Myelodysplasia

Carbon Monoxide to Prevent Lung Inflammation

A Study of Atezolizumab (an Engineered Anti-Programmed Death-Ligand 1 [PD-L1] Antibody) as Monotherapy or in Combination With Bevacizumab (Avastin®) Compared to Sunitinib (Sutent®) in Participants With Untreated Advanced Renal Cell Carcinoma

Screening for Age-Related Skeletal Muscle Dysfunction

The Mechanism of Action of the Unite Biomatrix in Diabetic Foot Ulcer

Safety and Efficacy of Lubiprostone in Pediatric Patients With Constipation

A Phase 3 Study of Ibrutinib (PCI-32765) Versus Ofatumumab in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia

Longitudinal Evaluation of [18F]GTP1 as a PET Radioligand for Imaging Tau in the Brain of Participants With Alzheimer's Disease Compared to Healthy Participants

Efficacy and Safety of IDP-121 and IDP-121 Vehicle Lotion in the Treatment of Acne Vulgaris

An Extension Study of ABT-199 in Subjects With Advanced Non-Hodgkin's Lymphoma

A Study to Describe Patterns of Care and Outcomes of Men Who Are at High Risk After Experiencing Biochemical Failure Following Definitive Prostate Cancer Therapy, Men With Castration-resistant Prostate Cancer and Men With Metastatic Prostate Cancer