Clinical Trials in Baltimore

Showing 10321-10340 of 17,842 trials

Cognitive, Behavioral, and Functional Change in Behavioral Variant Frontotemporal Dementia (bvFTD)

NCT03088956

The objectives of the study are to; (1) estimate the change in disease -related cognitive decline over 1 year on a battery of cognitive tests administered to participants with early-stage symptomatic Behavioral Variant Frontotemporal Dementia (bvFTD) phenotypic variant; (2) identify the cognitive test or brief battery of cognitive tests which are the most sensitive to detect bvFTD progression; (3) determine the optimal schedule of administration of cognitive tests to detect bvFTD progression; (4) evaluate the relationship between cognitive tests and measures of behavior, function, caregiver's burden, quality of life (QOL); and (5) obtain blood samples for genetic and exploratory biomarkers correlations.

Frontotemporal DementiaBehavioral Variant Frontotemporal Dementia

Biogen47 participantsStarted Jan 2018

Birmingham, Alabama, United States • Los Angeles, California, United States • Boca Raton, Florida, United States +9 more locations

TERMINATED< 1 mile

A Study of the Natural History of Leukocyte Chemotactic Factor 2 Amyloidosis (ALECT2) Disease

NCT03774784

The purpose of this study is to characterize the natural history of leukocyte chemotactic factor 2 amyloidotic (ALECT2) disease. In this observational study participants with ALECT2 disease will be enrolled. Participants, who have already reached end-stage renal disease (ESRD), will provide retrospective chart review data and biological specimens at baseline only. Other participants, in addition to retrospective chart review, will be followed prospectively.

AmyloidosisLeukocyte Chemotactic Factor 2 Amyloidosis

Alnylam Pharmaceuticals26 participantsStarted Jan 2019

Scottsdale, Arizona, United States • Tucson, Arizona, United States • Denver, Colorado, United States +28 more locations

Cognitive, Behavioral, and Functional Change in Behavioral Variant Frontotemporal Dementia (bvFTD)

A Study of the Natural History of Leukocyte Chemotactic Factor 2 Amyloidosis (ALECT2) Disease

Find Trials by Condition in Baltimore

A Phase 2b Study of Inhaled RVT-1601 for the Treatment of Persistent Cough in IPF

Radiation Therapy (RT) and Temozolomide (TMZ) in Treating Patients With Newly Diagnosed Glioblastoma or Gliosarcoma

T-DOC® NXT Clinical Investigation

Thrombogenicity Assessment in Patients Treated With Bioresorbable Vascular Scaffolds

A Study of Apixaban in Patients With Atrial Fibrillation, Not Caused by a Heart Valve Problem, Who Are at Risk for Thrombosis (Blood Clots) Due to Having Had a Recent Coronary Event, Such as a Heart Attack or a Procedure to Open the Vessels of the Heart

A Study of Ixekizumab (LY2439821) in TNF Inhibitor Experienced Participants With Radiographic Axial Spondyloarthritis

A Gene Therapy Study for Hemophilia B

Temsirolimus Adventitial Delivery to Improve Angiographic Outcomes Below the Knee (TANGO)

Phase 1/2a Dose-Escalation Study of CRLX301 in Patients With Advanced Solid Tumors

Oral Omadacycline vs. Oral Nitrofurantoin for the Treatment of Cystitis

Efficacy and Safety of NYX-2925 in Subjects With Neuropathic Pain Associated With Diabetic Peripheral Neuropathy

Different Doses of BI 1467335 Compared to Placebo in Patients With Clinical Evidence of NASH

Self-Management App for Patients With Left-Ventricular Assist Devices

Phase I Study of LDK378 in Pediatric, Malignancies With a Genetic Alteration in Anaplastic Lymphoma Kinase (ALK)

GSK2982772 Study in Subjects With Ulcerative Colitis

Study to Evaluate Arikayce™ in CF Patients With Chronic Pseudomonas Aeruginosa Infections

Dose Timing of D-Cycloserine to Augment CBT for Social Anxiety Disorder

An International Survey of the Occurrence of Cardiovascular Disease Among Patients With Type 2 Diabetes