Clinical Trials in Baltimore

Showing 9781-9800 of 23,476 trials

HBV-HIV Coinfection Research Network

NCT01924455

Despite effective ART that can suppress both HIV and HBV, HBV-related liver disease remains a significant co-morbidity in this population. Little is known about the histologic spectrum of liver disease, the significance of complete vs. incomplete HBV suppression, the utility of novel virologic and serum markers of disease severity, and the long-term renal and bone effects of TDF-based therapy. This proposal will address these important questions and impact the science and health of those coinfected with HBV-HIV.

Hepatitis BHuman Immunodeficiency Virus

Virginia Commonwealth University139 participantsStarted Apr 2014

San Francisco, California, United States • Baltimore, Maryland, United States • Bethesda, Maryland, United States +5 more locations

COMPLETEDNA< 1 mile

Acupuncture in Spinal Cord Injury Subjects

NCT03197675

Of the more than 250,000 Americans with severe spinal cord injury (SCI), 42,000 are military veterans. The Department of Veterans Affairs is the largest single network of SCI care providers in the nation. Patients with SCI experience functional disabilities as well as chronic pain. Studies show that individuals with SCI report pain refractory to conventional treatments. Civilian and veteran patients with SCI have associated pain with impairments in physical and cognitive function, sleep, employment, social relationships, community re-integration and quality of life. In a survey of individuals with SCI, those who used acupuncture experienced a reduction of pain symptoms lasting hours after treatment, with 27.3% reporting pain relief for days. A pilot study on the use of auricular acupuncture for neuropathic pain associated with SCI showed a greater reduction of pain as measured by the Numerical Rating Scale (NRS). A recent review of randomized controlled trials regarding the use of acupuncture in SCI found that only two of sixteen included studies were of high quality. There was limited evidence for the use of acupuncture in motor functional recovery, bladder function recovery, and in pain control related to SCI. Further high quality studies are needed. This proposal is for a phase II randomized clinical trial.

Spinal Cord Injuries

University of Maryland, Baltimore69 participantsStarted Mar 2018

Baltimore, Maryland, United States

HBV-HIV Coinfection Research Network

Acupuncture in Spinal Cord Injury Subjects

Find Trials by Condition in Baltimore

First-in-human Study of CCW702 in Patients With Metastatic Castration Resistant Prostate Cancer

Momelotinib Versus Ruxolitinib in Subjects With Myelofibrosis

Medication Adherence Research in COPD Patients

COVID Card Pilot Study to Detect Antibodies to SARS-CoV-2

rhBMP-2/CRM/CD HORIZON® Spinal System Pivotal Study

DuraMesh Laparotomy Closure Following Trauma and Emergency Surgery

Accessorized Pre-Filled Syringe to Autoinjector Pharmacokinetic Bridging Study in Anifrolumab

Multi-Component Early Intervention for Socially Inhibited Preschool Children

A Multi-Method Early Intervention Program for Inhibited and Anxious Preschoolers

Study to Evaluate the Efficacy and Safety of Remdesivir in Participants With Severely Reduced Kidney Function Who Are Hospitalized for Coronavirus Disease 2019 (COVID-19)

Safety, Tolerability, and Exploratory Efficacy of Adjunctive EQU-001 for Seizures in Adults With Epilepsy

Impact of Nilotinib on Safety, Tolerability, Pharmacokinetics and Biomarkers in Dementia With Lewy Bodies

Acute Effects of Added Sugar Intake on Cerebrovascular Function and Brain Integrity

Mechanisms of Impaired Brain Blood Flow With Aging

P3 Long Term Safety Study of Once Daily SB204 in Acne

Pilot Bi-Lateral Tubal Occlusion Trial for Female Permanent Contraception

Effectiveness of Early Intervention in an Underserved Population

Study of ASN003 in Subjects With Advanced Solid Tumors