Clinical Trials in Baltimore

Showing 9781-9800 of 17,842 trials

A Phase I Study to Assess the Safety of Pegcetacoplan (APL-2) as an Add-On to Standard of Care in Subjects With PNH

NCT02264639

This study will be the initial exploration of pegcetacoplan in patients with PNH. The assessments of the safety, tolerability, PK, and PD following administration of single and multiples doses of pegcetacoplan will guide decisions to further develop the drug.

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Apellis Pharmaceuticals, Inc.9 participantsStarted Feb 2015

Los Angeles, California, United States • Miami Lakes, Florida, United States • Louisville, Kentucky, United States +4 more locations

COMPLETEDPhase 3< 1 mile

Study of Safety and Efficacy of Brolucizumab 6 mg Drug Product Intended for Commercialization in Patients With nAMD

NCT03386474

The purpose of this extension study was to assess the safety and efficacy of the new formulation of brolucizumab 6 mg ophthalmic solution when given to the same patients who received brolucizumab in the core trial CRTH258A2301 (also known as CRTH258-C002). The medical condition treated in the core and extension trials was neo-vascular age-related macular degeneration (nAMD).

Neovascular Age-related Macular Degeneration

Novartis Pharmaceuticals151 participantsStarted Jan 2018

Peoria, Arizona, United States • Phoenix, Arizona, United States • Arcadia, California, United States +62 more locations

A Phase I Study to Assess the Safety of Pegcetacoplan (APL-2) as an Add-On to Standard of Care in Subjects With PNH

Study of Safety and Efficacy of Brolucizumab 6 mg Drug Product Intended for Commercialization in Patients With nAMD

Find Trials by Condition in Baltimore

Mirabegron For Erectile Dysfunction

A Fighting Chance: Pilot Study of a Group Mentoring Intervention for Assault Injured Youth

Validation of Coronary Calcium Subtraction to Improve Diagnostic Accuracy of Coronary CT Angiography

A Study of Acalabrutinib and Vistusertib in Subjects With Relapsed/Refractory B-cell Malignancies

Phase II Study of Axitinib (AG-013736) With Evaluation of the VEGF-pathway in Metastatic, Recurrent or Primary Unresectable Pheochromocytoma/Paraganglioma

Multicenter Study for Pediatric Subjects Evaluating Pharmacokinetics and Safety of EXPAREL

A Study in Maintenance Kidney Transplant Recipients Following Conversion to Nulojix® (Belatacept)-Based

A Study (Study 2) to Evaluate the Safety and Efficacy of FMX103 1.5% Topical Minocycline Foam in the Treatment of Facial Papulopustular Rosacea

Study to Assess Efficacy and Safety of Baloxavir Marboxil In Combination With Standard-of-Care Neuraminidase Inhibitor In Hospitalized Participants With Severe Influenza

Safety, Pharmacokinetics and Efficacy of Bimagrumab in Overweight and Obese Patients With Type 2 Diabetes

Pharmacodynamics, Safety, Tolerability, and Pharmacokinetics of Two Orally Inhaled Indacaterol Salts in Adult Subjects With Asthma.

Regorafenib+FOLFIRI Versus Placebo+FOLFIRI as 2nd Line Tx in Metastatic Colorectal Cancer

Safety, Tolerability, Pharmacokinetics and Efficacy of LMB763 in Patients With NASH

A Phase 3 Trial of Brentuximab Vedotin(SGN-35) Versus Physician's Choice (Methotrexate or Bexarotene) in Participants With CD30-Positive Cutaneous T-Cell Lymphoma (ALCANZA Study)

Evaluating Anatomic Versus Targeted Lead Placement for Burst Stimulation Therapy During the Trial

PAZIT Study for Children and Young Adults With Relapsed or Refractory Sarcoma

A Study of Oral LBH589 in Adult Patients With Advanced Hematological Malignancies

Korean Medicine for Symptomatic Lumbar Spinal Spondylolisthesis