Clinical Trials in Baltimore

Showing 9361-9380 of 23,476 trials

Oral Cannabidiol for Opioid Withdrawal

NCT04238754

This pilot study will examine the safety of the cannabinoid cannabidiol (Epidiolex) in a human laboratory model of clinically relevant withdrawal. The study will be a residential within-subject comparison; all participants will receive placebo dosing and active cannabidiol. Results may be used to support an R01 grant application to more closely examine this hypothesis.

Opioid WithdrawalOpioid CravingOpioid Use Disorder

Johns Hopkins University3 participantsStarted Nov 2020

Baltimore, Maryland, United States

COMPLETEDPhase 1< 1 mile

A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of PRV-3279 in Healthy Subjects

NCT03955666

This Phase 1b study will evaluate the safety of PRV-3279 in healthy adult subjects

Safety

Provention Bio, Inc.16 participantsStarted Aug 2019

Baltimore, Maryland, United States

TERMINATEDPhase 2< 1 mile

Oral SM-88 in Patients With Metastatic HR+/HER2- Breast Cancer

NCT04720664

This is a phase II single arm, open-label study of SM-88 used with methoxsalen, phenytoin, and sirolimus (MPS) in metastatic HR+/HER2- breast cancer. It is designed to determine efficacy, defined as the objective response rate (ORR) of this investigational treatment. It is hypothesized that SM-88 used with MPS will lead to significant anti-tumor responses with acceptable toxicities in patients with metastatic HR+/HER2- breast cancer.

Breast CancerMetastatic Breast CancerHormone Receptor Positive Breast Carcinoma

Georgetown University11 participantsStarted Sep 2021

Washington D.C., District of Columbia, United States • Washington D.C., District of Columbia, United States • Baltimore, Maryland, United States +2 more locations

Oral Cannabidiol for Opioid Withdrawal

A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of PRV-3279 in Healthy Subjects

Oral SM-88 in Patients With Metastatic HR+/HER2- Breast Cancer

Find Trials by Condition in Baltimore

Vision Performance Evaluation of TECNIS EYHANCE™ With TECNIS SIMPLICITY™ Compared to TECNIS® 1-piece Intraocular Lenses

A Phase 2 Study of Sitravatinib in Combination With PD-(L)1 Checkpoint Inhibitor Regimens in Patients With Advanced or Metastatic Urothelial Carcinoma

Safety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis (MIRA-3)

Adrabetadex to Treat Niemann-Pick Type C1 (NPC1) Disease

Phase II Study to Assess Safety and Efficacy of SL-1002 for Osteoarthritic Knee Pain

Study of Heart Failure Hospitalizations After Aquapheresis Therapy Compared to Intravenous (IV) Diuretic Treatment

An Efficacy, Safety, and Tolerability Study Comparing Dolutegravir Plus Lamivudine With Dolutegravir Plus Tenofovir/Emtricitabine in Treatment naïve HIV Infected Subjects (Gemini 1)

Evaluation of VGX-3100 and Electroporation Alone or in Combination With Imiquimod for the Treatment of HPV-16 and/or HPV-18 Related Vulvar HSIL (Also Referred as: VIN 2 or VIN 3)

Investigation of Novel Surgical Imaging for Tumor Excision

Arimoclomol in Amyotropic Lateral Sclerosis

Maximizing Outcomes in Treating Acute Migraine

Study of AMG 650 in Adult Participants With Advanced Solid Tumors

TYRX™ Pocket Health Study

A Study of TRS01 in Subjects With Active Non-infectious Anterior Uveitis Including Subjects With Uveitic Glaucoma

Safety And Efficacy Study Of Avelumab Plus Chemotherapy With Or Without Other Anti-Cancer Immunotherapy Agents In Patients With Advanced Malignancies

Resynchronization/Defibrillation for Ambulatory Heart Failure Trial

Intraperitoneal vs Intravenous Chemotherapy Following Neoadjuvant Chemotherapy in Ovarian Cancer