Clinical Trials in Baltimore

Showing 8621-8640 of 17,842 trials

ExAblate Transcranial MRgFUS of the Globus Pallidum for Treatment of Parkinson's Disease

NCT02263885

The proposed study will evaluate the safety, and initial efficacy of using the ExAblate Transcranial to create a unilateral lesion in the globus pallidus as an adjunct to PD medications in subjects who are over 30 years of age and considered medication-refractory with advanced idiopathic Parkinson's disease (PD).

Parkinson's Disease

InSightec20 participantsStarted Apr 2015

Stanford, California, United States • Baltimore, Maryland, United States • Boston, Massachusetts, United States +2 more locations

COMPLETEDPhase 1< 1 mile

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of BIIB078 in Adults With C9ORF72-Associated Amyotrophic Lateral Sclerosis

NCT03626012

The primary objective of this study is to evaluate the safety and tolerability of BIIB078 in adults with C9ORF72-Amyotrophic Lateral Sclerosis (ALS). The secondary objectives of this study are to evaluate the pharmacokinetic profile of BIIB078 and to evaluate the effects of BIIB078 on clinical function. As the first-in-human study, the study enrolls a small number of participants in each cohort. Every participant in a cohort is treated with the same dose or placebo. The study is designed to evaluate and confirm the safety of each dose before enrolling and exposing new participants to a higher dose in the next cohort.

Amyotrophic Lateral Sclerosis

Biogen106 participantsStarted Sep 2018

La Jolla, California, United States • Los Angeles, California, United States • Palo Alto, California, United States +18 more locations

ExAblate Transcranial MRgFUS of the Globus Pallidum for Treatment of Parkinson's Disease

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of BIIB078 in Adults With C9ORF72-Associated Amyotrophic Lateral Sclerosis

Find Trials by Condition in Baltimore

Prone Position and Respiratory Outcomes in Non-Intubated COVID-19 PatiEnts The "PRONE" Study

Clinical Study of a Diagnostic Device for NG, TV and CT in Women

Phase 4 IOP Signals Associated With ILUVIEN®

EPOCH Chemotherapy +/- IL-12 for Previously Untreated and EPOCH Plus Rituximab for Previously Treated Patients With AIDS-Associated Lymphoma

CAR T Cell Receptor Immunotherapy for Patients With B-cell Lymphoma

BN-Brachyury, Entinostat, Adotrastuzumab Emtansine and M7824 in Advanced Stage Breast Cancer (BrEAsT)

Renal Denervation in Patients With Uncontrolled Blood Pressure

Congenital Heart Initiative-Redefining Outcomes and Navigation to Adult Centered Care

Treatments for Anxiety: Meditation and Escitalopram

A Depot Formulation of Sunitinib Malate (GB-102) Compared to Aflibercept in Subjects With Wet AMD

Efficacy and Safety of Prochymal® Infusion in Combination With Corticosteroids for the Treatment of Newly Diagnosed Acute Graft Versus Host Disease (GVHD)

PV-10 vs Chemotherapy or Oncolytic Viral Therapy for Treatment of Locally Advanced Cutaneous Melanoma

A Study to Evaluate the Long-Term Safety of Topical Administration of FMX103 in the Treatment of Moderate to Severe Papulopustular Rosacea

A Study of Idasanutlin With Cytarabine Versus Cytarabine Plus Placebo in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML)

A Study to Compare the Efficacy and Safety of Topical Administration of FMX-101 for Treatment of Moderate-to-Severe Acne

Clinical Evaluation of a Daily Wear Reusable Multifocal Optical Design in a Presbyopic Population

BATTLE-2 Program: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non-Small Cell Lung Cancer

Evaluation of a Daily Disposable Novel Multifocal Contact Lens in a Myopic Population