Clinical Trials in Baltimore

Showing 7161-7180 of 17,842 trials

A New Treatment for Mechanical Nasal Obstruction

NCT03456115

The research team has developed a prototype for an investigational mechanical nasal dilator and the investigators aim to evaluate its efficacy. Specifically, the investigators wish to address the following research questions: 1) How does mechanical nasal obstruction affect patients' lives? The investigators aim to answer this question with use of validated questionnaires. 2) How do currently available mechanical nasal dilators affect objective and subjective findings related to nasal obstruction? This will be evaluated with objective nasal airflow testing and with modifications to validated questionnaires 3) How does the investigational team's novel device affect these same outcome measures? 4) Do patients find the investigational device subjectively comfortable and efficient?

Nasal Obstruction

Johns Hopkins University36 participantsStarted Oct 2018

Baltimore, Maryland, United States

COMPLETED< 1 mile

Multi-center Prospective Study to Evaluate Outcomes of the Moderate to Severely Calcified Coronary Lesions (MACE)

NCT01930214

The objective of this study is to assess the current standard of care treatment outcome in none/mild, moderate and severely calcified coronary lesions using: * A composite of MACE at 30-day and one (1) year post procedure, and * Procedural and lesion success

Coronary Artery Disease

Abbott Medical Devices350 participantsStarted Sep 2013

Little Rock, Arkansas, United States • Glendale, California, United States • Hartford, Connecticut, United States +31 more locations

A New Treatment for Mechanical Nasal Obstruction

Multi-center Prospective Study to Evaluate Outcomes of the Moderate to Severely Calcified Coronary Lesions (MACE)

Find Trials by Condition in Baltimore

Expanded Access to Voxelotor for Patients With Sickle Cell Disease Who Have No Alternative Treatment Options

Comparative Study to Evaluate Efficacy and Safety of Gepotidacin to Nitrofurantoin in Treatment of Uncomplicated Urinary Tract Infection (UTI)

Human Perception on Medical Extended Reality Devices

Early Diagnosis of Sickle Acute Chest Syndrome Using a Combination of Plasma Bimarkers and Chest Imaging

A Trial of NT-I7 in COVID-19 (SPESELPIS)

Study of Iomab-B vs. Conventional Care in Older Subjects With Active, Relapsed or Refractory Acute Myeloid Leukemia

Safety and Performance of Journey II XR Total Knee System

Study of Intravenous ATYR1923 (Efzofitimod) for Pulmonary Sarcoidosis

First in Human Study to Evaluate the Safety and Tolerability of EYP-1901 in Patients With Wet Age Related Macular Degeneration (wAMD)

Evaluate the Safety and Efficacy of OAS in Treating Severely Calcified Coronary Lesions

Relapse Prevention Study in Patients With Schizophrenia

PDGeneration: Mapping the Future of Parkinson's Disease

A Gene Therapy Study for Homozygous Familial Hypercholesterolemia (HoFH)

A Clinical Trial of Intravenous (IV) Ganaxolone in Women With Postpartum Depression

A Safety and Tolerability Study of ARGX-113 in Patients With Myasthenia Gravis Who Have Generalized Muscle Weakness.

Study on the Effectiveness and Safety of the Combination of the Two Drugs Regorafenib and Nivolumab in Patients With Colorectal Cancer (Cancer of the Colon or Rectum Classified as Proficient Mismatch Repair and Microsatellite Stable)

Deep Brain Stimulation (DBS) for the Treatment of Parkinson's Disease

Efficacy and Safety of GSK3196165 (Otilimab) Versus Placebo and Sarilumab in Participants With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Biological Disease-modifying Antirheumatic Drug (DMARDs) and/or Janus Kinase (JAK) Inhibitors