Clinical Trials in Baltimore

Showing 6841-6860 of 23,476 trials

Study of High-Dose-Rate Endorectal Brachytherapy (HDRBT) in the Treatment of Locally Advanced Low Rectal Cancer

NCT01226979

This research is being done to see how effective high-dose rate endorectal brachytherapy (HDRBT) is in treating cancer of the lowest part of the bowel (rectum). In this study we want to try to decrease side effects and shorten the course of radiation treatment for patients with cancer of their rectum by using a high-dose rate endorectal brachytherapy (HDRBT). This is a different form of radiation than what is normally given (CRT). With HDRBT, the radiation is given through an applicator placed into the bowel next to the tumor. The radiation is directed at the tumor and a small area around it.

Rectal Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins16 participantsStarted Oct 2010

Baltimore, Maryland, United States

COMPLETEDPhase 2< 1 mile

A118G SNP and OPRM1 Gene Opioid-Mediated Effects in Humans

NCT02360371

Within-subject, double-blind, placebo-controlled examination of opioid abuse potential in healthy individuals as a function of A118G SNP on the OPRM1 gene.

Opioid SensitivityIndividual DifferenceAbuse Opioids

Johns Hopkins University100 participantsStarted Apr 2015

Baltimore, Maryland, United States

Study of High-Dose-Rate Endorectal Brachytherapy (HDRBT) in the Treatment of Locally Advanced Low Rectal Cancer

A118G SNP and OPRM1 Gene Opioid-Mediated Effects in Humans

Find Trials by Condition in Baltimore

Azacitidine and Combination Chemotherapy in Treating Infants With Acute Lymphoblastic Leukemia and KMT2A Gene Rearrangement

Bupropion-Enhanced Contingency Management (CM) for Cocaine Dependence

A Study to Evaluate AAV9 Neutralizing Antibody Seroconversion in Household Contacts.

Thriving Together: Supporting Resilience in the Healthcare Workforce

NXT Post-Market Clinical Follow-up

A Phase II, Randomized, Double-blind, Placebo-controlled Study to Assess MEDI3506 in Participants With COPD and Chronic Bronchitis

Title: Safety and Feasibility of Individualized Low Amplitude Seizure Therapy (iLAST)

Effects of Prism Adaption and rTMS on Brain Connectivity and Visual Representation

A Phase 2 Study of IW-3300 for the Treatment of Bladder Pain in Subjects With Interstitial Cystitis/Bladder Pain Syndrome

Mind Over Matter for Black and African American Women: A Single Arm Trial Examining Feasibility and Acceptability of a Supportive Intervention

Multicenter Hologic Tomosynthesis Study

First-in-human Study of DB-1305/BNT325 for Advanced/Metastatic Solid Tumors

A Safety Trial of Lisocabtagene Maraleucel (JCAR017) for Relapsed and Refractory (R/R) B-cell Non-Hodgkin Lymphoma (NHL) in the Outpatient Setting (TRANSCEND-OUTREACH-007)

Testing the Addition of a Radiation Sensitizing Drug, IPdR, to the Usual Chemotherapy Treatment (Capecitabine) During Radiation Therapy for Rectal Cancer

Oral EPI-7386 in Patients with Castration-Resistant Prostate Cancer

S1014 Abiraterone Acetate in Treating Patients With Prostate Cancer Who Have Undergone Initial Hormone Therapy

An Observational Study to Assess Change in Disease Activity and Adverse Events of Upadacitinib in Adult Participants With Moderate to Severe Ulcerative Colitis (UC) in Real-World Practice

Phase 2 Study of Efficacy and Safety of AK120, in Subjects With Moderate-to-Severe Atopic Dermatitis