Clinical Trials in Baltimore

Showing 6501-6520 of 23,476 trials

Study of Efficacy, Safety and Tolerability of CMK389 in Patients With Chronic Pulmonary Sarcoidosis

NCT04064242

The purpose of this proof of concept study was to determine whether CMK389 displays the safety and efficacy profile to support further development in chronic pulmonary sarcoidosis.

Pulmonary Sarcoidosis

Novartis Pharmaceuticals62 participantsStarted Sep 2020

Birmingham, Alabama, United States • Gainesville, Florida, United States • Kansas City, Kansas, United States +19 more locations

COMPLETED< 1 mile

MRI to Characterize and Predict CF Liver Disease in PUSH Cohort

NCT02979340

Specific Aim 1. Determine if valid results of non-sedated MRI based assessments of liver stiffness and lipid content can be obtained in more than 90% of children and young adults with cystic fibrosis. Specific Aim 2. Determine hepatic lipid content using the HepaFat sequence and liver stiffness using MRE. Investigators will compare the results obtained by MRI with PUSH study grayscale ultrasounds in CF patients with normal, heterogeneous, homogeneous or nodular (cirrhotic) pattern on ultrasound. Specific Aim 3. Creation of an imaging core lab to centralize evaluation of MR imaging data, allow for remote image upload, electronic data storage, and remote image viewing/interpretation. This infrastructure will be utilized to standardize image post processing. Specific Aim 4. Using the longitudinal PUSH study, determine if MRI based imaging improves discrimination of subjects at risk for progression to advanced CF liver disease (development of cirrhosis) compared to using US imaging alone

Cystic Fibrosis Liver DiseasePancreatic Insufficiency

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)115 participantsStarted Jan 2017

Aurora, Colorado, United States • Atlanta, Georgia, United States • Indianapolis, Indiana, United States +5 more locations

Study of Efficacy, Safety and Tolerability of CMK389 in Patients With Chronic Pulmonary Sarcoidosis

MRI to Characterize and Predict CF Liver Disease in PUSH Cohort

Find Trials by Condition in Baltimore

Prediction by Ultrasound of the Risk of Hepatic Cirrhosis in Cystic Fibrosis

Working Memory and Physical Exercise Training in Patients With Mild Cognitive Impairment

Safety Study of AG-120 or AG-221 in Combination With Induction and Consolidation Therapy in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) With an IDH1 and/or IDH2 Mutation

The SHUNT-V Study for Varices

Filgrastim-Mobilized Stem Cells for Transplantation Using Unrelated Donors

An 8-week Open-label Study of an Accelerated and Slower Switching to Xanomeline/Trospium Following Atypical Antipsychotic Treatment in Participants With Schizophrenia

A Dose Escalation and Expansion Study of GIGA-564 in Participants With Locally Advanced or Metastatic Solid Tumor Malignancies

Electrical Stimulation Effect on Ankle Instability During Walking in Virtual Reality Setup

The ME&MG Digital Solution for Autonomous Assessment of Myasthenia Gravis

A Phase 3 Long-term Extension Study to Assess the Long-term Safety and Efficacy of Pegtibatinase Treatment in Participants ≥5 to ≤65 Years of Age With Classical Homocystinuria (HCU) (ENSEMBLE)

A Study of Pazopanib With or Without Abexinostat in Patients With Locally Advanced or Metastatic Renal Cell Carcinoma (RENAVIV)

Leading in MPNs Beyond Ruxolitinib in Combo With T-Regs

YIV-906 (Formerly PHY906/KD018) With Sorafenib in HBV(+) Hepatocellular Carcinoma (HCC)

Metformin Hydrochloride in Preventing Breast Cancer in Patients With Atypical Hyperplasia or In Situ Breast Cancer

FlowMet-R Blood Flow Measurement for the Diagnosis of Peripheral Artery Disease and Critical Limb Ischemia

Safety and Tolerability of BION-1301 in Healthy Volunteers and Adults With IgA Nephropathy (IgAN)

Multi-Center Evaluation of Feasibility of SPECT Measurement of Myocardial Blood Flow and Reserve

Ureteral Stent Placement After Ureteroscopy for Renal Stones: A Randomized Controlled Trial