Clinical Trials in Baltimore

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CT TAVR Abdomen Study

NCT05758701

A standard polyenergetic CT (computed tomography) procedure utilizes 100 ml of iodinated contrast. A recent world-wide shortage of iodine based intravenous contrast has highlighted the need to search for alternative methods or doses. Reducing iodinated IV contrast dose can mitigate IV contrast supply shortages and enable significant cost savings for the radiology practice and hospital system. In addition, decreased IV contrast dose can potentially reduce the rate of acute kidney injury, specifically in patients with decreased renal function. The purpose of the study is to determine whether low IV contrast dose CT with monoenergetic reconstruction can be use for presurgical planning of transcatheter valve replacement (TAVR) procedure.

Transcatheter Aortic Valve Replacement

University of Maryland, Baltimore164 participantsStarted Sep 2023

Baltimore, Maryland, United States

RECRUITINGPhase 2< 1 mile

DALY II USA/ MB-CART2019.1 for DLBCL

NCT04792489

DALY II USA is a phase II, multi-center, single arm study to evaluate the efficacy, safety, and pharmacokinetics of zamtocabtagene autoleucel (MB-CART2019.1) in patients with relapsed and/or refractory diffuse large B cell lymphoma (DLBCL) after receiving at least two lines of therapy. Additional cohorts include subjects with B-cell primary or secondary central nervous system (CNS) lymphoma (PCNSL) and (SCNSL), mantle cell lymphoma (MCL) and Richter's transformation (RT) after receiving at least one line of therapy.

Refractory Diffuse Large B Cell Lymphoma (DLBCL)Relapsed Diffuse Large B Cell LymphomaHigh Grade B-cell Lymphoma (HGBCL)+5 more

Miltenyi Biomedicine GmbH248 participantsStarted May 2021

Gilbert, Arizona, United States • Phoenix, Arizona, United States • La Jolla, California, United States +22 more locations

CT TAVR Abdomen Study

DALY II USA/ MB-CART2019.1 for DLBCL

Find Trials by Condition in Baltimore

Prophylaxis and Treatment of COVID-19

MERIDIAN: A Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Adults With Amyotrophic Lateral Sclerosis (ALS)

Clinical Trial Readiness to Solve Barriers to Drug Development in FSHD

A Study to Verify the Clinical Benefit of Aducanumab in Participants With Early Alzheimer's Disease

Genes and Environment in Multiple Sclerosis

Treatment of Persistent Atrial Fibrillation With Sphere-9 Catheter and Affera Mapping and Ablation System

A Multiple-dose Study of ASP8374, an Immune Checkpoint Inhibitor, as a Single Agent and in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors

HiLo: Pragmatic Trial of Higher vs Lower Serum Phosphate Targets in Patients Undergoing Hemodialysis

A Trial of Setanaxib in Patients With Primary Biliary Cholangitis (PBC) and Liver Stiffness

Laser Ablation of Abnormal Neurological Tissue Using Robotic NeuroBlate System

Autologous Adipose-derived Stromal Vascular Fraction for Treatment of Knee Osteoarthritis

Safety and Efficacy of GS-100 Gene Therapy in Patients With NGLY1 Deficiency

Study of REM-422 in Patients With AML or Higher Risk MDS

Comparative Study of Conventional MR Images With Synthetically Reconstructed MR Images of the Brain

A Study to Investigate the Efficacy, Safety, and Tolerability of JNJ-42165279 in Adolescent and Adult Participants With Autism Spectrum Disorder

Predictive Analytics and Clinical Decision Support to Improve PrEP Prescribing

A Study of BI-1206 in Combination With Rituximab With or Without Acalabrutinib in Subjects With Indolent B-Cell NHL

Phase 2b Study of MBS2320 in Participants With Methotrexate-Refractory RA