Clinical Trials in Baltimore

Showing 4541-4560 of 23,476 trials

Randomized Salvage Radiation Therapy Plus Enzalutamide Post Prostatectomy

NCT02203695

The primary hypothesis of this study is that outcomes for patients with biochemically recurrent prostate cancer following radical prostatectomy will be improved by the addition of enzalutamide for 6-months compared to standard-of-care salvage radiation therapy to allow for further study in the definitive phase III setting. This study builds on the prior success of high-dose bicalutamide (for 24 months) when combined with salvage external radiation therapy (XRT), while using a newer more potent anti-androgen for a shorter duration of time (6 months) in an effort to minimize adverse effects.

Adenocarcinoma of the Prostate

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins86 participantsStarted Mar 2015

Washington D.C., District of Columbia, United States • Chicago, Illinois, United States • Lafayette, Indiana, United States +6 more locations

Active Not RecruitingNA< 1 mile

Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Severe, Symptomatic Aortic Stenosis in Intermediate Risk Subjects Who Need Aortic Valve Replacement (SURTAVI).

NCT01586910

The purpose of the study is to investigate the safety and efficacy of transcatheter aortic valve implantation (TAVI) in patients with severe, symptomatic Aortic Stenosis (AS) at intermediate surgical risk by randomizing patients to either Surgical Aortic Valve Replacement (SAVR) or TAVI with the Medtronic CoreValve® System. Single Arm: The purpose of this trial is to evaluate the safety and effectiveness of transcatheter aortic valve implementation (TAVI) in patients with severe symptomatic Aortic Stenosis (AS) at intermediate surgical risk with TAVI. This is a non-randomized phase of the pivotal clinical trial.

Severe Aortic Stenosis

Medtronic Cardiovascular1,746 participantsStarted Apr 2012

Phoenix, Arizona, United States • Hollywood, California, United States • La Jolla, California, United States +83 more locations

Randomized Salvage Radiation Therapy Plus Enzalutamide Post Prostatectomy

Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Severe, Symptomatic Aortic Stenosis in Intermediate Risk Subjects Who Need Aortic Valve Replacement (SURTAVI).

Find Trials by Condition in Baltimore

Resiliency in Older Adults Undergoing Bone Marrow Transplant

Substudy 02C: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents or Pembrolizumab Alone in Participants With Stage III Melanoma Who Are Candidates for Neoadjuvant Therapy (MK-3475-02C/KEYMAKER-U02)

Phase 2b Study of GSK4532990 in Adults With NASH

Efficacy and Safety of Deucravacitinib Versus Placebo in Participants With Moderate-to-severe Scalp Psoriasis

COVID-19 Associated Lymphopenia Pathogenesis Study in Blood

Oral Metformin for Treatment of ABCA4 Retinopathy

Addressing Genomic Disparities in Cancer Survivors

NPWT Reduction Mammaplasty

Study to Evaluate VT3989 in Patients With Metastatic Solid Tumors

ZIP Study-OL Study of Safety, PK, Efficacy, PD, Immunogenicity of ATB200/AT2221 in Pediatrics Aged 0 to < 18 y.o. w/LOPD

A Clinical Trial to Investigate Long-term Safety, Tolerability, and Efficacy of Weekly Subcutaneous Doses With TransCon CNP in Children and Adolescents With Achondroplasia

CLIP-IT Post-Market Study

Study to Investigate the Efficacy and Safety of Dupilumab in Pediatric Patients With Active Eosinophilic Esophagitis (EoE)

Gemcitabine, Paclitaxel and Oxaliplatin (GemPOx)

Evaluation of the Clinical Performance of Daily Disposable Silicone Hydrogel Multifocal Toric Contact Lenses

Bortezomib After Combination Chemotherapy, Rituximab, and an Autologous Stem Cell Transplant in Treating Patients With Mantle Cell Lymphoma

Randomized Blinded Evaluation of the Effects of TENS and IFC Compared to a Sham Device and SOC in Patients With Non-Specific CLBP

Stryker's Surgeon iD Mandible Reconstruction Plates: A Retrospective Post Market Follow Up