Clinical Trials in Baltimore

Showing 3641-3660 of 20,142 trials

The Natural History of TRPV4 Neuropathy

NCT05600764

The goal of this research is to document the natural history of neuropathy in patients with a confirmed genetic mutation in the TRPV4 gene. The investigators are searching for patients willing to participate in a 6-year long study to document the symptoms of TRPV4-associated disease and their progression over time. Participation requires annual study visits at Johns Hopkins for adult and juvenile participants.

TRPV4 Gene Mutation

Johns Hopkins University70 participantsStarted Dec 2023

Baltimore, Maryland, United States

COMPLETEDPhase 3< 1 mile

Clinical Trial Evaluating ITI-007 (Lumateperone) as a Monotherapy for the Treatment of Bipolar Depression

NCT02600494

The study will evaluate the efficacy and safety of ITI-007 (Lumateperone) in patients diagnosed with Bipolar I or Bipolar II disorder having a major depressive episode. The study will be conducted in two parts, Part A and Part B. Part A is a randomized, double-blind, placebo-controlled study. In Part B, patients who safely complete participation in part A may be enrolled in an open-label extension.

Bipolar Depression

Intra-Cellular Therapies, Inc.554 participantsStarted Dec 2015

Little Rock, Arkansas, United States • Rogers, Arkansas, United States • Cerritos, California, United States +52 more locations

The Natural History of TRPV4 Neuropathy

Clinical Trial Evaluating ITI-007 (Lumateperone) as a Monotherapy for the Treatment of Bipolar Depression

Find Trials by Condition in Baltimore

Pivotal, Open-label, Randomized Study of Radiosurgery With or Without Tumor Treating Fields (TTFields) for 1-10 Brain Metastases From Non-small Cell Lung Cancer (NSCLC).

A Study to Assess Long-term Safety, Tolerability, and Efficacy of Rocatinlimab in Adult and Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD)

Androgen Reduction in Congenital Adrenal Hyperplasia, Phase 1

Allogeneic Hematopoietic Stem Cell Transplantation With Briquilimab-Based Conditioning in Participants With GATA2 Deficiency

ZILRETTA in Subjects With Shoulder Osteoarthritis

Zilebesiran as Add-on Therapy in Patients With Hypertension Not Adequately Controlled by a Standard of Care Antihypertensive Medication (KARDIA-2)

Combining a Smartphone App With Medications to Manage Heavy Drinking

A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension

Long Term Follow-up Study of Type-1 Gaucher Subjects Post FLT201 Dose (GALILEO-2)

A Modular Phase 1/2 Study With CT7439 in Participants With Solid Malignancies

A Study of LY3405105 in Participants With Advanced Cancer

A Study to Describe the Characteristics, Health Care Interventions and Outcomes of Patients With Major Bleedings in the Presence of Factor Xa Inhibitor Treatment

Randomized Study Comparing Two Dosing Schedules for Hypofractionated Image-Guided Radiation Therapy

Selinexor, Carfilzomib, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma

To Evaluate Safety and Tolerability of the Fixed- Dose Combination of Obeticholic Acid and Bezafibrate

A Phase 2a Proof-of-Concept Trial of Bempikibart (ADX-914) for the Treatment of Severe Alopecia Areata (SIGNAL-AA)

Multicenter Assessment of the Pancreas in Type 1 Diabetes

Phase 3, Randomized, Placebo-Controlled Study of Tinlarebant to Explore Safety and Efficacy in Adolescent Stargardt Disease