Clinical Trials in Baltimore

Showing 3261-3280 of 23,476 trials

Immunobiology Blood and Tissue Collection of Upper Aerodigestive Malignancies

NCT05995821

This research is being done to collect and store biological specimens (biospecimens) from people with cancer, regardless of tumor type, who are receiving treatments known or thought to have an effect on the immune system. The goal of this discovery and exploratory study is to: * Understand changes in the immune system associated with various cancer treatments, in order to better design new therapies or tests to predict how these treatments might work. * Identify risk factors for those who go on to develop side effects from immunotherapy. * Identify the molecular features associated with response and resistance to cancer therapies and immunotherapy using integrative genomic and immune repertoire characterization. * Capture and characterize systemic tumor burden by minimally invasive analyses of circulating tumor DNA. Participants may be asked to: * Donate samples of tumor, blood, lymph nodes, white blood cells, mouth cells (buccal smears) scraped from the inside of participant's cheek, urine, saliva, or other tissue samples. * Complete questionnaires about immunotherapy side effects at baseline and with follow-up appointments. * Undergo knee x-rays. * Allow the use of demographic and clinical information.

Head and Neck CancerLung CancerGastrointestinal Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins1,250 participantsStarted Aug 2016

Baltimore, Maryland, United States

Active Not Recruiting36 miles

Diet, Hepcidin, and Chemotherapy RDI

NCT06483997

This prospective, observational cohort study will evaluate the extent of associations between self-reported pro- or anti- inflammatory dietary intake patterns for one month before induction chemotherapy for gynecological cancer or neo/adjuvant chemotherapy for breast cancer and baseline serum hepcidin concentrations. Associations between hepcidin concentration and relative dose intensity (RDI) of chemotherapy will also be evaluated.

Breast Cancer FemaleOvarian CancerFallopian Tube Cancer+3 more

George Washington University100 participantsStarted Aug 2024

Washington D.C., District of Columbia, United States

Immunobiology Blood and Tissue Collection of Upper Aerodigestive Malignancies

Diet, Hepcidin, and Chemotherapy RDI

Find Trials by Condition in Baltimore

A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis

Palliative Care Needs of Children With Rare Diseases and Their Families

Evaluation of Revumenib in Participants With Colorectal Cancer and Other Solid Tumors

A Study of PHN-010 in Patients With Advanced Solid Tumors

Assessing an Oral EGFR Inhibitor, Sunvozertinib in Patients Who Have Advanced Non-small Cell Lung Cancer With EGFR or HER2 Mutation (WU-KONG1)

Vaginal Care System for Menopausal Women With Urinary Tract Infections

An Open Label, Randomized Study of Neoadjuvant Nivolumab and Chemotherapy, With or Without Sub-ablative Stereotactic Body Radiation Therapy, for Resectable Stage IIA to IIIB Non-small Cell Lung Cancer

FOCUS: A Phase I/II First in Human Study to Evaluate the Safety and Efficacy of GT005 Administered in Subjects With Dry AMD

Phase III Study Assessing the Efficacy and Safety of Pegcetacoplan in Patients With C3 Glomerulopathy or Immune-Complex Membranoproliferative Glomerulonephritis

A Study in Patients Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study

First-in-Human Study of ADCE-D01 in Soft Tissue Sarcoma

A Study of a Novel Iron-based Phosphate Binder AP301 in Patients With Hyperphosphatemia in the U.S. and China

A Clinical Trial of PRAX-562 in Subjects With Developmental and Epileptic Encephalopathies (DEE)

The Thrive Study: Improving Multimodal Physical Function in Adults With Heterogenous Chronic Pain

Phase 1/2a Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of WEF-001 as Monotherapy in Advanced KRAS-Mutant Solid Tumours.

Primary Radiotherapy Versus Primary Surgery for HPV-Associated Oropharyngeal Cancer

A Study With CIT-013 in HS Patients

BCL2i CLAG-M in R/R Acute Myeloid Leukemia