Clinical Trials in Austin

Showing 3841-3860 of 9,923 trials

A Study of Single Ascending Doses of IW-3300 in Healthy Volunteers

NCT05188261

This is a first-in-human study to evaluate the safety and tolerability of single ascending doses of IW-3300. The study drug will be administered rectally as a low-volume (20 mL) enema. Study participants will be randomized in a 3:1 ratio to receive a single dose of IW-3300 or placebo. Up to 5 different doses of IW-3300 will be studied. Safety reviews will be conducted before proceeding to each higher dose.

Healthy Volunteers

Ironwood Pharmaceuticals, Inc.32 participantsStarted Jan 2022

Austin, Texas, United States

COMPLETEDPhase 1< 1 mile

Effect of Therapeutic and Supratherapeutic Oral Doses of GSK3640254 on Cardiac Conduction Compared to Placebo and a Single Oral Dose of Moxifloxacin

NCT04563845

This study will aim to evaluate the effect of therapeutic and supratherapeutic oral doses of GSK3640254 on cardiac conduction compared to placebo and a single oral dose of Moxifloxacin in healthy adult participants. The study has 2 parts: Part 1 will determine the supratherapeutic dose for Part 2, which will be the main corrected QT interval (QTc) study. Part 1 will evaluate once daily (QD) dosing of GSK3640254 or placebo and Part 2 will investigate the safety, tolerability and Pharmacokinetics (PK) of GSK3640254 doses on cardiac conduction as compared to placebo and a single oral dose of Moxifloxacin in healthy adult participants. Moxifloxacin will be included as a positive control.

HIV Infections

ViiV Healthcare50 participantsStarted Nov 2020

Austin, Texas, United States

UNKNOWNPhase 3< 1 mile

Postpartum Management of Hypertension in Pregnancy With Hydrochlorothiazide

NCT03298802

Postpartum prophylactic HCTZ administration for prevention and relapse of preeclampsia or gestational hypertension.

Pre-EclampsiaGestational HypertensionSuperimposed Pre-Eclampsia+3 more

The University of Texas Medical Branch, Galveston612 participantsStarted Nov 2017

Austin, Texas, United States • Galveston, Texas, United States

A Study of Single Ascending Doses of IW-3300 in Healthy Volunteers

Effect of Therapeutic and Supratherapeutic Oral Doses of GSK3640254 on Cardiac Conduction Compared to Placebo and a Single Oral Dose of Moxifloxacin

Postpartum Management of Hypertension in Pregnancy With Hydrochlorothiazide

Find Trials by Condition in Austin

Nivolumab Maintenance Therapy After Autologous Stem Cell Transplant in Hodgkin Lymphoma Pts at Relapse/Progression Risk

Intraoperative Laser Speckle Contrast Imaging of Cerebral Blood Flow

A Study to Investigate Aqueous Humor and Multimodal Imaging Biomarkers in Treatment-Naïve Participants With Diabetic Macular Edema Treated With Faricimab

Childhood Trauma, Exercise, and Cognition

Cognitive Screening Made Easy for PCPs

Assessing Clinical Outcomes in Alzheimer's Disease Agitation

A Study to Asses Efficacy, Safety and Tolerability of Monthly Long-acting IM Injection of GA Depot in Subjects With RMS

Phase I-Ib/II Study of MBG453 as Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies

20-valent Pneumococcal Conjugate Vaccine Safety and Immunogenicity Study of a 4-Dose Series in Healthy Infants

Chronic Pain Master Protocol (CPMP): A Study of LY3016859 in Participants With Chronic Low Back Pain

Approaches and Decisions for Acute Pediatric TBI Trial

HD IL-2 + Ipilimumab in Patients With Metastatic Melanoma

A Phase II Open Label Study of BMS-582664 in Locally Advanced or Metastatic Hepatocellular Cancer

A Study to Test How Well Different Doses of BI 1569912 Are Tolerated and How Well They Work in People With Depression Who Take Anti-depressive Medication

Effect of Tiotropium (Spiriva) on Exercise Tolerance in COPD Patients

Altis® 522 Trial - Treatment of Female Stress Urinary Incontinence

International Lung Screen Trial (ILST)