Clinical Trials in Atlanta

Showing 1161-1180 of 9,468 trials

RNS System LGS Feasibility Study

NCT05339126

To generate preliminary safety and effectiveness data for brain-responsive neurostimulation of thalamocortical networks as an adjunctive therapy in reducing the frequency of generalized seizures in individuals 12 years of age or older with Lennox Gastaut Syndrome (LGS) who are refractory to antiseizure medications. The intent is to determine the feasibility and the optimal design of a subsequent pivotal study in order to expand the indication for use for the RNS System as a treatment for patients with medically intractable LGS.

EpilepsyLennox Gastaut SyndromeLennox-Gastaut Syndrome, Intractable+2 more

NeuroPace24 participantsStarted Oct 2022

Birmingham, Alabama, United States • San Francisco, California, United States • Atlanta, Georgia, United States +3 more locations

COMPLETEDPhase 1/2< 1 mile

A Study of the Safety and Tolerability of GTX-102 in Children With Angelman Syndrome

NCT04259281

The primary objective of the study is to evaluate the safety and tolerability of multiple-ascending doses of GTX-102 administered by intrathecal (IT) injection to participants with Angelman Syndrome (AS).

Angelman Syndrome

Ultragenyx Pharmaceutical Inc74 participantsStarted Feb 2020

Los Angeles, California, United States • San Diego, California, United States • Atlanta, Georgia, United States +22 more locations

RNS System LGS Feasibility Study

A Study of the Safety and Tolerability of GTX-102 in Children With Angelman Syndrome

Find Trials by Condition in Atlanta

Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Endotoxemic Septic Shock in a Randomized, Open-Label Study

Pharmacokinetic and Safety Study of MRX-2843 in Adolescents and Adults With Relapsed/Refractory AML, ALL, or MPAL

Use of the Impella BTR™ in Patients With Heart Failure: An Early Feasibility Study

A Study to Assess Adjuvant Immunotherapy With Nivolumab Plus Relatlimab Versus Nivolumab Alone After Complete Resection of Stage III-IV Melanoma

Gemcitabine Hydrochloride and Cisplatin With or Without Nab-Paclitaxel in Treating Patients With Newly Diagnosed Advanced Biliary Tract Cancers

Auryon Atherectomy System With Standard Balloon Angioplasty Versus Standard Balloon Angioplasty Alone

Study of Bitopertin to Evaluate the Safety, Tolerability, Efficacy, and PPIX Concentrations in Participants With EPP

A Study to Evaluate the Efficacy and Safety of Golcadomide in Combination With Rituximab in Participants With Newly Diagnosed Advanced Stage Follicular Lymphoma

Rehabilitation for Arthritis of The Knee: mainTaining Improvement for Veterans

STimulation to Activate RespIration

Supporting Parents in Affirming Their Children's Experiences of Stigma

A Study Assessing Adverse Event and How Oral ABBV-453 Moves Through the Body in Adult Participants With Relapsed or Refractory (R/R) Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

Study of Onvansertib in Combination With FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab Versus FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab for First-Line Treatment of Metastatic Colorectal Cancer in Adult Participants With a KRAS or NRAS Mutation

A Study of the Efficacy and Safety of Belimumab in Adults With Systemic Sclerosis Associated Interstitial Lung Disease

Radiation- and Alkylator-free Bone Marrow Transplantation Regimen for Patients With Dyskeratosis Congenita

Human Laboratory Study of Apremilast for Alcohol Use Disorder

A Phase 1b/2, Multicenter, Open-label Study of ACP-196 in Subjects With Recurrent Glioblastoma Multiforme (GBM)

A Study of Relatlimab in Combination With Nivolumab in Participants With Advanced Liver Cancer Who Have Never Been Treated With Immuno-oncology Therapy After Prior Treatment With Tyrosine Kinase Inhibitors