Clinical Trials in Atlanta

Showing 9181-9200 of 19,805 trials

Study of AZD5991 Alone or in Combination With Venetoclax in Relapsed or Refractory Haematologic Malignancies.

NCT03218683

This study is a multicenter, open-label, nonrandomized, sequential group, dose-escalation study to assess safety, tolerability, pharmacokinetics and preliminary anti-tumor activity of ascending doses of AZD5991 in subjects with relapsed or refractory hematologic malignancies Part 1 of the study is monotherapy dose escalation. Closed November 2020 Part 2 of the study is monotherapy expansion groups for relapsed/refractory chronic lymphocytic leukaemia (CLL), AML/ myelodysplastic syndromes (MDS), and multiple myeloma (MM). Closed November 2020 Part 3 is a sequential, dose-escalation study of the combination of AZD5991 and venetoclax in subjects with relapsed/refractory AML

Relapsed or Refractory Acute Myeloid Leukemia (AML)

AstraZeneca70 participantsStarted Aug 2017

Orange, California, United States • Aurora, Colorado, United States • Atlanta, Georgia, United States +7 more locations

COMPLETEDPhase 2< 1 mile

An Efficacy Study of MORAb-009 (Amatuximab) in Subjects With Pleural Mesothelioma

NCT00738582

This research is being done to find out if pemetrexed and cisplatin work better when given together with an experimental drug called MORAb-009 in patients with malignant pleural mesothelioma.

Malignant Pleural Mesothelioma

Morphotek89 participantsStarted Dec 2008

Birmingham, Alabama, United States • La Jolla, California, United States • Los Angeles, California, United States +25 more locations

Study of AZD5991 Alone or in Combination With Venetoclax in Relapsed or Refractory Haematologic Malignancies.

An Efficacy Study of MORAb-009 (Amatuximab) in Subjects With Pleural Mesothelioma

Find Trials by Condition in Atlanta

Long Term Follow Up Study to COMP 001 And COMP 003 Trials (P-TRD LTFU)

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation.

Open Label Study of Long Term Evaluation Against LDL-C Trial

KEAPSAKE: A Study of Telaglenastat (CB-839) With Standard-of-Care Chemoimmunotherapy in 1L KEAP1/NRF2-Mutated, Nonsquamous NSCLC

A Study of Telaglenastat (CB-839) in Combination With Palbociclib in Patients With Solid Tumors

A Double-blind Study of Paclitaxel in Combination With Reparixin or Placebo for Metastatic Triple-Negative Breast Cancer

Effects of Pneumatic Vitreolysis on Vitreomacular Traction

A Multiple Dose Study of Repeat Intravitreal Injections of GEM103 in Dry Age-related Macular Degeneration

Corticosteroid Lumbar Epidural Analgesia for Radiculopathy

Study Comparing Carfilzomib, Lenalidomide, and Dexamethasone (CRd) vs Lenalidomide and Dexamethasone (Rd) in Subjects With Relapsed Multiple Myeloma

A Study of Cobimetinib Plus Atezolizumab Versus Pembrolizumab in Participants With Previously Untreated Advanced BRAFv600 Wild-Type Melanoma

Study of Denosumab in Subjects With Giant Cell Tumor of Bone

Study of Romosozumab (AMG 785) in Tibial Diaphyseal Fractures Status Post Intramedullary Nailing

A Study of Epacadostat in Combination With Pembrolizumab and Chemotherapy in Participants With Advanced or Metastatic Solid Tumors (ECHO-207/KEYNOTE-723)

SAR3419 in Acute Lymphoblastic Leukemia

An Open Label, Multicenter Study to Evaluate the Pharmacokinetics, Efficacy and Safety of ASCENIV™ (IGIV) in Pediatric Subjects With Primary Immunodeficiency Diseases (PIDD)

Marketability of a Technology-based Intervention to Increase HPV Vaccination

Radiation and Cetuximab Plus Intratumoral EGFR Antisense DNA in Locally Advanced Head and Neck Squamous Cell Carcinoma