Clinical Trials in Atlanta

Showing 5321-5340 of 14,993 trials

HB-302/HB-301 Therapy in Participants With Metastatic Castration-Resistant Prostate Cancer

NCT05553639

This is a first-in-human Phase 1/2, multinational, multicenter, open-label study of HB-302/HB-301 alternating 2-vector therapy in participants with metastatic castration-resistant prostate cancer (mCRPC) comprising 2 phases: a Phase 1 Dose Escalation and recommended Phase 2 dose (RP2D) Confirmation, and a Phase 2 Dose Expansion.

Prostate Cancer Metastatic

Hookipa Biotech GmbH12 participantsStarted May 2023

Duarte, California, United States • San Marcos, California, United States • Miami, Florida, United States +7 more locations

TERMINATEDPhase 3< 1 mile

An Open-label Study to Assess the Long-term Safety, Tolerability, Effectiveness, and Durability of Effect of KarXT in Patients With DSM-5 Diagnosis of Schizophrenia

NCT05643170

This is a Phase 3b, 3-year, open-label, multi-center study in which patients with DSM-5 diagnosis of schizophrenia whose current medication(s) is not well tolerated and/or clinical symptoms are not well controlled will be switched to receive KarXT. The primary objectives of the study are to assess the long-term safety and tolerability of KarXT and assess effectiveness, persistence, and durability of effect of KarXT through the Investigator Assessment Questionnaire (IAQ) and Clinical Global Impression - Severity of Illness (CGI-S) scale in patients with a diagnosis of schizophrenia. The secondary objectives are to further assess the effectiveness using the Clinical Global Impression, Global Improvement (CGI-I), long-term safety and tolerability of KarXT, and evaluation of scores from multiple additional patient scales and assessments throughout the study.

Schizophrenia

Karuna Therapeutics, Inc., a Bristol Myers Squibb company4 participantsStarted Nov 2022

Atlanta, Georgia, United States • Louisville, Kentucky, United States • Columbus, Ohio, United States +2 more locations

HB-302/HB-301 Therapy in Participants With Metastatic Castration-Resistant Prostate Cancer

An Open-label Study to Assess the Long-term Safety, Tolerability, Effectiveness, and Durability of Effect of KarXT in Patients With DSM-5 Diagnosis of Schizophrenia

Find Trials by Condition in Atlanta

Biphasic Effects of Acute Alcohol Intoxication on Bystander Intervention

A Study to Examine the Efficacy and Safety of Anti-Fel d 1 Antibodies Injections in Cat-allergic Adolescent and Adult Patients With Allergic Rhinitis Who Live With a Cat

Study of ALVR106 in Patients With Respiratory Viral Infections After Hematopoietic Cell and Solid Organ Transplant

PRE-VENT Study in Hospitalized Patients With Severe COVID-19 With or Without Cancer

Cardiovascular Outcome Study to Evaluate the Effect of Obicetrapib in Patients With Cardiovascular Disease

A Study of BMN 255 in Participants With Non-Alcoholic Fatty Liver Disease And Hyperoxaluria

Dry Needling and Spinal Manipulation vs. Conventional PT for Lumbar Spinal Stenosis

Safety and Efficacy Study of Sofpironium Bromide in Subjects With Axillary Hyperhidrosis (BBI-4000-CL-301)

Bridge to HOPE: Hypothermic Oxygenated Perfusion Versus Cold Storage Prior to Liver Transplantation

Trim II for Noninvasive Lipolysis and Circumference Reduction of Abdomen.

Upamostat, a Serine Protease Inhibitor, or Placebo for Treatment of COVID-19 Disease

Exploring the Efficacy and Safety of Siponimod in Patients With Secondary Progressive Multiple Sclerosis (EXPAND)

Long-Term Safety of ARQ-154 Foam in Subjects With Seborrheic Dermatitis

Cellular Immunotherapy in Recipients of HLA-matched, Living Donor Kidney Transplants

A Phase 3 Study of UGN-102 for Low-Grade Intermediate-Risk Non-Muscle Invasive Bladder Cancer

Trial for Treatment Refractory Trigeminal Neuralgia

A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

Phase I Study of Cell Therapies for the Treatment of Patients With Relapsed or Refractory AML or High-risk MDS