Clinical Trials in Atlanta

Showing 2881-2900 of 9,468 trials

Safety Evaluation of the Advanced Hybrid Closed Loop (AHCL) System

NCT03959423

This study is a Safety Evaluation of the Advanced Hybrid Closed Loop (AHCL) System in Type 1 Adult and Pediatric Subjects.

Type 1 Diabetes Mellitus

Medtronic Diabetes288 participantsStarted Jul 2019

Little Rock, Arkansas, United States • La Jolla, California, United States • Torrance, California, United States +14 more locations

COMPLETEDPhase 2< 1 mile

Emergency Department-Initiated Buprenorphine Validation Network Trial

NCT04225598

This study will (1) recruit, train and provide resources to approximately 30 Emergency Department (ED) sites throughout the U.S. using implementation facilitation strategies to provide ED-initiated buprenorphine (BUP) for patients presenting with opioid use disorder (OUD) who are not receiving medications for opioid use disorder (MOUD). Once implementation is adequately achieved, the sites will (2) conduct a randomized controlled trial (RCT) to compare the effectiveness of sublingual buprenorphine (SL-BUP) versus extended-release buprenorphine (XR-BUP) on ED patients' engagement in formal addiction treatment 7-days after their ED visit. In addition, in an ancillary component of the study, the investigators will (3) assess the use of XR-BUP in ED patients with Clinical Opioid Withdrawal Scale (COWS) scores \< 8 in a case series to potentially expand the eligibility of patients in the larger RCT to those presenting with little to no opioid withdrawal symptoms. Finally, the investigators will (4) develop and validate ED electronic health record (EHR) opioid-related phenotypes, both of which will inform the main RCT.

Opioid-use Disorder

Yale University2,000 participantsStarted Jul 2020

Oakland, California, United States • San Leandro, California, United States • New Haven, Connecticut, United States +32 more locations

Safety Evaluation of the Advanced Hybrid Closed Loop (AHCL) System

Emergency Department-Initiated Buprenorphine Validation Network Trial

Find Trials by Condition in Atlanta

Expanded Access Study for the Treatment of Patients With Commercially Out-of-Specification Brexucabtagene Autoleucel

A Study of TAK-861 in Participants With Narcolepsy Type 2

SomaSignal Tests on Medical Management and Change in Risk in Patients With Diabetes

Pepinemab in Combination With Pembrolizumab in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

Evaluate the Efficacy and Safety of ACP-044 in Subjects With Pain Associated With Osteoarthritis of the Knee

Study of AxoGuard® Nerve Cap and Neurectomy for Treatment of Symptomatic Neuroma & Prevention of Recurrent Neuroma Pain

A Study Evaluating Targeted Therapies in Participants Who Have Advanced Solid Tumors With Genomic Alterations or Protein Expression Patterns Predictive of Response

Safety, Tolerability, and Pharmacokinetics of Clesrovimab (MK-1654) in Infants (MK-1654-002)

A Study Evaluating the Safety and Efficacy of BEAM-201 in Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LL)

Long-term Follow-up Study for Patients Treated With CLBR001 CAR-T

StrataPATH™ (Precision Indications for Approved Therapies)

Study of Onvansertib in Combination With FOLFIRI and Bevacizumab Versus FOLFIRI and Bevacizumab for Second Line Treatment of Metastatic Colorectal Cancer in Participants With a Kirsten Rat Sarcoma Virus Gene (KRAS) or Neuroblastoma-RAS (NRAS) Mutation

HOPE-Duchenne (Halt cardiomyOPathy progrEssion in Duchenne)

Nemaline Myopathy Clinical Research Network (NM-CTRN)

Expanded Access Treatment with [Lu-177]-PNT2002 for Adult Patients with Prostate-Specific Membrane Antigen (PSMA)-Positive Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Anti-CD137 and Anti-CTLA-4 Monoclonal Antibody in Patients With Advanced Cancer

Study of Nanrilkefusp Alfa Alone and With Pembrolizumab in Adult Patients With Advanced/Metastatic Solid Tumors

Study of SFA002 in Patients with Mild to Moderate Psoriasis Plaques