Clinical Trials in Arizona

Showing 1581-1600 of 8,032 trials

A Cardiac Liability Study of Varegacestat in Healthy Participants

NCT06855264

This clinical study is designed to study the effect of a single dose of varegacestat on cardiac repolarization in healthy adult participants.

Healthy Volunteer

Immunome, Inc.32 participantsStarted Feb 2025

Tempe, Arizona, United States

COMPLETEDPhase 242 miles

Anti-viral Therapy in Alzheimer's Disease

NCT03282916

Anti-viral therapy in Alzheimer's disease will investigate the efficacy of treating patients with mild Alzheimer's disease with the U.S.A marketed generic anti-viral drug Valtrex (valacyclovir, 500mg oral tablet). Valacyclovir, titrated to 4 grams per day, repurposed to treat Alzheimer's disease, will be compared to matching placebo in the treatment of 130 mild AD patients (65 valacyclovir, 65 placebo) who test positive for herpes simplex virus-1 (HSV1) or herpes simplex virus-2 (HSV2). The study will be a randomized, double-blind, 18-month Phase II proof of concept trial.

Alzheimer DiseaseHerpes Simplex 1Herpes Simplex 2

Columbia University120 participantsStarted Feb 2018

Phoenix, Arizona, United States • New York, New York, United States • New York, New York, United States

COMPLETEDPhase 342 miles

A Study to Evaluate the Efficacy and Safety of BLI5100 in Patients With Erosive Esophagitis

NCT05587309

The objective of the Healing Phase of the study is to evaluate the safety and efficacy of up to 8 weeks of once daily oral administration of BLI5100 versus a PPI control in healing EE. The objective of the Maintenance Phase of the study is to evaluate the safety and efficacy of 24 weeks of once daily oral administration of BLI5100 (low or high dose) versus a PPI control in the maintenance of healed EE.

Erosive Esophagitis

Braintree Laboratories1,250 participantsStarted Oct 2022

Homewood, Alabama, United States • Huntsville, Alabama, United States • Peoria, Arizona, United States +119 more locations

A Cardiac Liability Study of Varegacestat in Healthy Participants

Anti-viral Therapy in Alzheimer's Disease

A Study to Evaluate the Efficacy and Safety of BLI5100 in Patients With Erosive Esophagitis

Find Trials by Condition in Arizona

A Clinical Trial on Safety and Efficacy of CBT-001 in Patients With Pterygium

A Study Evaluating the Long-term Safety and Efficacy of VX-445 Combination Therapy

Treatment of Refractory Nausea and Vomiting in Patients With Breast Cancer

Phase 2a Study of VX-147 in Adults With APOL1-mediated Focal Segmental Glomerulosclerosis

Beta-Agonist Versus OnabotulinumtoxinA Trial for Urgency Urinary Incontinence

A Dose Escalation Study of SHP2 Inhibitor in Patients With Solid Tumors Harboring KRAS of EGFR Mutations

Study of OCA in Combination With BZF Evaluating Efficacy, Safety and Tolerability in Participants With PBC

A Study of AZD3427 in Participants With Heart Failure and Pulmonary Hypertension Group 2

A Study of Cabozantinib Compared With Placebo in Subjects With Radioiodine-refractory Differentiated Thyroid Cancer Who Have Progressed After Prior Vascular Endothelial Growth Factor Receptor (VEGFR) -Targeted Therapy

Brentuximab Vedotin and Nivolumab for the Treatment of Patients With Relapsed/Refractory Classical Hodgkin Lymphoma

A Study of BH-30236 in Relapsed/ Refractory Acute Myelogenous Leukemia and Higher Risk Myelodysplastic Syndrome

Metabolic Mechanisms Induced by Enteral DHA and ARA Supplementation in Preterm Infants

An Early Feasibility Study Evaluation of an Implant Free Interatrial Shunt to Improve Heart Failure

Diagnosis and Treatment of CAD in Severe PAD After Lower Extremity Revascularization

Study to Evaluate Safety and Efficacy of VX-661 in Combination With Ivacaftor in Subjects With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation With an Open-Label Expansion

Stereotactic Body Radiotherapy (SBRT) for Early Treatment of Oligometastatic Adenoid Cystic Carcinoma: The SOLAR Trial

Natural History and Biospecimen Acquisition for Children and Adults With Rare Solid Tumors