Clinical Trials in Arizona

Showing 6101-6120 of 12,706 trials

Struvite Stones Antibiotic Study

NCT02375295

The aim of this research is to determine an effective antibiotic regimen following definitive surgical therapy of kidney stones caused by bacterial infection (struvite stones).

Kidney Stones

University of British Columbia28 participantsStarted Mar 2015

Scottsdale, Arizona, United States • San Diego, California, United States • Baltimore, Maryland, United States +9 more locations

COMPLETEDPhase 331 miles

Phase 3 Study of Pexidartinib for Pigmented Villonodular Synovitis (PVNS) or Giant Cell Tumor of the Tendon Sheath (GCT-TS)

NCT02371369

This is a Phase 3 clinical study, which aims to evaluate the effectiveness of an investigational drug called pexidartinib for the treatment of certain tumors for which surgical removal could cause more harm than good. The main purpose of this study is to gather information about the investigational drug pexidartinib, which may help to treat tumors of pigmented villonodular synovitis (PVNS) or giant cell tumor of the tendon sheath (GCT-TS). The study consists of two parts with a follow-up period. In Part 1, eligible study participants will be assigned to receive either pexidartinib or matching placebo for 24 weeks. A number of assessments will be carried out during the course of the study, including physical examinations, blood tests, imaging studies, electrocardiograms, and questionnaires. MRI scans will be used to evaluate the response of the tumors to the treatment. Some subjects, assigned to placebo in Part 1 transitioned to pexidartinib for Part 2. Then a protocol amendment was written to allow only pexidartinib patients to continue into Part 2. Part 2 is a long-term treatment phase in which all participants receive open-label pexidartinib. There was also a follow-up period added to Part 2.

Pigmented Villonodular SynovitisGiant Cell Tumors of the Tendon SheathTenosynovial Giant Cell Tumor

Daiichi Sankyo120 participantsStarted May 2015

Scottsdale, Arizona, United States • Los Angeles, California, United States • Palo Alto, California, United States +36 more locations

Struvite Stones Antibiotic Study

Phase 3 Study of Pexidartinib for Pigmented Villonodular Synovitis (PVNS) or Giant Cell Tumor of the Tendon Sheath (GCT-TS)

Find Trials by Condition in Arizona

Multicenter Study to Evaluate Safety and Efficacy of WC3011 (Estradiol Vaginal Cream) in Postmenopausal Women

Myelofibrosis and Essential Thrombocythemia Observational Study (MOST)

Extension Study to Evaluate the Long-Term Safety and Tolerability of Oral Atogepant for the Prevention of Migraine in Participants With Episodic Migraine

Study to Evaluate the Efficacy and Safety of Perampanel as Monotherapy or First Adjunctive Therapy in Subjects With Partial Onset Seizures With or Without Secondarily Generalized Seizures or With Primary Generalized Tonic-Clonic Seizures

Renew NCP-5 for the Treatment of Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild Dementia of the Alzheimer's Type

Effects of Oral Levosimendan (ODM-109) on Respiratory Function in Patients With ALS

Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome: ARISE-3

Safety and Efficacy of NBI-98854 in Pediatric Subjects With Tourette Syndrome

Dehydrated Human Umbilical Cord Allograft in the Management of Diabetic Foot Ulcers

Assessment of Tecfidera® in Radiologically Isolated Syndrome (RIS)

A Study to Compare Efficacy and Safety of Trifarotene Cream When Used With an Oral Antibiotic for the Treatment of Severe Acne Vulgaris (AV)

Bi 671800 in Asthmatic Patients on Inhaled Corticosteroids

Multicenter Selective Lymphadenectomy Trial II (MSLT-II)

Study to Evaluate Exemestane With and Without Entinostat (SNDX-275) in Treatment of Postmenopausal Women With Advanced Breast Cancer

Physiologic Assessment of Coronary Stenosis Following PCI

EndoPredict® Extended Endocrine Trial (EXET)

A Study to Assess the Safety of GRF6021 Infusions in Subjects With Parkinson's Disease and Cognitive Impairment

Subtotal Resection of Large Acoustic Neuromas With Possible Stereotactic Radiation Therapy