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Browse 8,272 clinical trials for ulcerative colitis. Find studies that match your criteria and connect with research centers.
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NCT07104760
Peri-implantitis is a pathological condition characterized by the inflammation of peri-implant connective tissues and progressive alveolar bone loss. There is a global concern about the increasing prevalence of this disease, which may affect up to 43% of implants in function. This cohort study will evaluated the long term follow up of a randomized, controlled, double-blind placebo study that evaluated the regenerative treatment of peri-implant diseases with surgical debridement and Er,Cr:YSGG AG laser associated with systemic antibiotics. A total of 80 subjects with peri-implantitis (PD\>5mm, BoP and/or sup, bone loss \>3mm) will be treated reavluated after 10years follow-up. Clinical, radiographic, and microbiological parameters will be recorded at baseline and 120 months follow-up. The primary outcome variable of this trial was be the difference between groups for the change in clinical attachment level from baseline to 6 months. We did consider composite outcomes, although not as the primary outcome. We also aim to evaluate the number and percentage of patients (and implants) reaching the following clinical endpoint for treatment: Probing depth \< 5mm, absence of bleeding on probing and no further bone loss (Heitz-Mayfield and Mombelli, 2014). The secondary variables will be the differences between groups in PI, GI, BOP, SUP and PD and microbial profile.
NCT07247591
The aim of this study is to define the starting and ending points of the adductor canal in adductor canal block (ACB) applications through distance measurements relative to the anterior superior iliac spine (ASIS) and the adductor tubercle. These measurements are performed using ultrasound (USG) and correlated with cadaveric data. Key research questions addressed include: * Can the start and end points of the adductor canal be formulated along a line drawn between the ASIS and the adductor tubercle? * Is there a definable relationship between the block application site and anatomical landmarks such as the vastoadductor membrane (VAM), the apex of the femoral triangle, and other adjacent structures that facilitates localization? By validating ultrasound measurements with cadaveric findings, the study aims to provide researchers with a more predictable and reliable method for determining the optimal site for adductor canal block administration.